US StockDetailed Quotes

Provided by Tiger Trade Technology Pte. Ltd.

Crescent Biopharma Inc

19.46

-0.5300-2.65%

Volume:233.14K

Turnover:4.55M

Market Cap:722.82M

PE:-2.63

High:19.90

Open:19.65

Low:19.16

Close:19.99

52wk High:27.41

52wk Low:8.72

Shares:37.14M

Float Shares:15.95M

Volume Ratio:0.54

T/O Rate:1.46%

Dividend:- -

Dividend Rate:- -

EPS(TTM):-7.4105

EPS(LYR):-12.8150

ROE:-160.75%

ROA:-69.15%

PB:9.96

PE(LYR):-1.52

Loading ...

Overview Company News Filings

Major Issues Report

8-K - Current report

Beneficial Ownership Change

SC 13D/A [Amend] - General statement of acquisition of beneficial ownership

Beneficial Ownership Change

SC 13D/A [Amend] - General statement of acquisition of beneficial ownership

Major Issues Report

8-K - Current report

Beneficial Ownership Change

SC 13D/A [Amend] - General statement of acquisition of beneficial ownership

Major Issues Report

8-K - Current report

Beneficial Ownership Change

SC 13D - General statement of acquisition of beneficial ownership

Beneficial Ownership Change

SC 13D/A [Amend] - General statement of acquisition of beneficial ownership

Major Issues Report

8-K - Current report

Beneficial Ownership Change

SC 13D/A [Amend] - General statement of acquisition of beneficial ownership

Major Issues Report

8-K/A [Amend] - Current report

Major Issues Report

8-K - Current report

Beneficial Ownership Change

SC 13D/A [Amend] - General statement of acquisition of beneficial ownership

Major Issues Report

8-K - Current report

Quarterly Report

10-Q - Quarterly report [Sections 13 or 15(d)]

Beneficial Ownership Change

SC 13D/A [Amend] - General statement of acquisition of beneficial ownership

[Rev.]Annual Report

10-K/A [Amend] - Annual report [Section 13 and 15(d), not S-K Item 405]

Beneficial Ownership Change

SC 13D/A [Amend] - General statement of acquisition of beneficial ownership

Major Issues Report

8-K - Current report

Annual Report

10-K - Annual report [Section 13 and 15(d), not S-K Item 405]

{"basename":"","ssrTDKData":{"titleTemplate":"%s - Tiger Brokers","title":"Tiger Brokers HK | Online Trading in stocks, bonds & ETFS","description":"Discover Tiger Brokers HK, an online trading platform for stocks&ETFs, options&futures, bonds and crypto. Open an account to enjoy low commission trading today!","keywords":"tiger trading,tiger security,tiger broker hk,tigers co ltd,tiger trade hk,tiger brokers hk,stock broker,securities broker,online brokerage,hong kong broker,hk broker,online stock trading,online trading platform,stock trading platforms,trading application,stock trading,stock trading hong kong,buying stocks in hong kong,tiger brokers","social":{"ogDescription":"Discover Tiger Brokers HK, an online trading platform for stocks&ETFs, options&futures, bonds and crypto. Open an account to enjoy low commission trading today!","ogImage":"https://c1.itigergrowtha.com/portal5/static/media/og-logo.0a0bd8dc.png","ogUrl":"https://www.atigrnest.com/stock/CBIO/filings?page=5"},"companyName":"Tiger Brokers"},"pageData":{"isMobile":false,"isTiger":false,"isTTM":true,"region":"HKG","license":"TBHK","edition":"fundamental","symbol":"CBIO","isAnalysisPage":false},"__swrFallback__":{"@#url:\"https://hq.skytigris.cn/stock_info/detail/global\",params:#delay:false,,method:\"POST\",data:#items:@#symbol:\"CBIO\",,,,,undefined,":{"symbol":"CBIO","market":"US","secType":"STK","nameCN":"Crescent Biopharma Inc","latestPrice":19.46,"timestamp":1789070400000,"preClose":19.99,"halted":0,"volume":233136,"delay":0,"changeRate":-0.02651325662831404,"floatShares":15953500,"shares":37143940,"eps":-7.4105,"marketStatus":"Pre-Mkt","change":-0.53,"latestTime":"09-11 05:10:32 EDT","open":19.65,"high":19.895,"low":19.16,"amount":4552510.318128,"amplitude":0.036768,"askPrice":30.39,"askSize":100,"bidPrice":7.79,"bidSize":200,"shortable":3,"etf":0,"ttmEps":-7.4105,"tradingStatus":1,"nextMarketStatus":{"tag":"Open","tradingStatus":2,"beginTime":1789133400000},"marketStatusCode":1,"adr":0,"adrRate":0,"listingDate":1389330000000,"exchange":"NASDAQ","adjPreClose":19.46,"postHourTrading":{"tag":"盘后","latestPrice":19.46,"preClose":19.46,"latestTime":"19:30 EDT","volume":1663,"amount":32361.6,"timestamp":1789083005411,"change":0,"changeRate":0,"amplitude":0},"volumeRatio":0.5368531583979466,"impliedVol":0.3193,"impliedVolPercentile":0.25},"@#url:\"https://hq.skytigris.cn/stock_info/fundamental/all\",params:#delay:false,,method:\"POST\",data:#items:@#symbol:\"CBIO\",,,,,undefined,":{"symbol":"CBIO","floatShares":15953500,"roa":"-69.15%","roe":"-160.75%","lyrEps":-12.814991,"volumeRatio":0.5368531583979466,"shares":37143940,"dividePrice":0,"high":19.895,"amplitude":0.036768,"preClose":19.99,"low":19.16,"week52Low":8.72,"pbRate":"9.96","psRate":"60.83","week52High":27.41,"institutionHeld":0.0724,"latestPrice":19.46,"committee":0.333333,"eps":-7.4105,"divideRate":0,"volume":233136,"delay":0,"ttmEps":-7.4105,"open":19.65,"prevYearClose":11.86,"prevWeekClose":20.88,"prevMonthClose":16.6,"prevQuarterClose":18,"fiveDayClose":18.54,"twentyDayClose":16.43,"sixtyDayClose":18.19},"@#url:\"https://hq.skytigris.cn/fundamental/corporate_actions/details/CBIO\",params:#limit:5,,,undefined,":[{"market":"US","date":"2026-07-30","symbol":"CBIO","fiscalQuarterEnding":"2026/06","expectedEps":-0.78,"name":null,"time":"Pre-MKt","type":"earning","dateTimestamp":1785384000000,"reportTimeType":"pre","actualEps":-0.74},{"market":"US","date":"2026-04-29","symbol":"CBIO","fiscalQuarterEnding":"2026/03","expectedEps":-0.85,"name":null,"time":"Post-Mkt","type":"earning","dateTimestamp":1777435200000,"reportTimeType":"post","actualEps":-0.7},{"market":"US","date":"2026-02-26","symbol":"CBIO","fiscalQuarterEnding":"2025/12","expectedEps":-2.22,"name":null,"time":"Pre-MKt","type":"earning","dateTimestamp":1772082000000,"reportTimeType":"pre","actualEps":-4.01},{"market":"US","date":"2025-11-06","symbol":"CBIO","fiscalQuarterEnding":"2025/09","expectedEps":-1.01,"name":null,"time":"Pre-MKt","type":"earning","dateTimestamp":1762405200000,"reportTimeType":"pre","actualEps":-1.27},{"market":"US","date":"2025-07-31","symbol":"CBIO","fiscalQuarterEnding":"2025/06","expectedEps":-2.69,"name":null,"time":"","type":"earning","dateTimestamp":1753934400000,"reportTimeType":"","actualEps":-4.93}],"@#url:\"https://hq.skytigris.cn/fundamental/dividend/history\",params:#symbol:\"CBIO\",market:\"US\",,,undefined,":[],"@#url:\"https://hq.skytigris.cn/fundamental/estimate/recommendation\",params:#symbol:\"CBIO\",market:\"US\",delay:false,,,undefined,":{"strongBuy":0.375,"buy":0.5,"hold":0.125,"sell":0,"strongSell":0,"meanLabel":"BUY","meanPercent":0.5,"analysts":8,"updateTime":1780372800000},"@#url:\"https://hq.skytigris.cn/value_analysis/stock/CBIO\",params:#withQuantilePoint:true,period:\"5year\",factor:\"peRate\",delay:false,algorithm:1,,,undefined,":{"brief":{"id":"CBIO","date":"2026-09-10","current":-2.626004,"percent":0.041463,"low":-7.394562,"twenty":-3.55915,"median":-0.979043,"eighty":-0.169318,"high":2.563796,"avg":-1.539041,"sd":2.153177,"marketCap":855593229},"quantilePoints":[{"date":"2021-09-17","current":-2.101704,"twenty":-4.26328,"median":-2.208025,"eighty":-1.2153,"marketCap":162474331},{"date":"2021-09-24","current":-1.923181,"twenty":-4.26328,"median":-2.208025,"eighty":-1.2153,"marketCap":148673422},{"date":"2021-10-01","current":-1.647282,"twenty":-4.26328,"median":-2.208025,"eighty":-1.2153,"marketCap":127344746},{"date":"2021-10-08","current":-1.562077,"twenty":-4.254957,"median":-2.206531,"eighty":-1.215339,"marketCap":120757948},{"date":"2021-10-15","current":-1.622937,"twenty":-4.254957,"median":-2.206531,"eighty":-1.215339,"marketCap":125462804},{"date":"2021-10-22","current":-1.407898,"twenty":-4.254957,"median":-2.206531,"eighty":-1.215339,"marketCap":108838982},{"date":"2021-10-29","current":-1.334866,"twenty":-4.254957,"median":-2.206531,"eighty":-1.217573,"marketCap":103193156},{"date":"2021-11-05","current":-1.253719,"twenty":-4.254957,"median":-2.206531,"eighty":-1.230021,"marketCap":96920016},{"date":"2021-11-12","current":-0.620853,"twenty":-4.254957,"median":-2.206531,"eighty":-1.236189,"marketCap":53710598},{"date":"2021-11-19","current":-0.475624,"twenty":-4.254957,"median":-2.206531,"eighty":-1.236189,"marketCap":41146716},{"date":"2021-11-26","current":-0.45384,"twenty":-4.254957,"median":-2.206531,"eighty":-1.236189,"marketCap":39262133},{"date":"2021-12-03","current":-0.395748,"twenty":-4.254957,"median":-2.206531,"eighty":-1.236189,"marketCap":34236580},{"date":"2021-12-10","current":-0.395748,"twenty":-4.246633,"median":-2.205037,"eighty":-1.233979,"marketCap":34236580},{"date":"2021-12-17","current":-0.366703,"twenty":-4.246633,"median":-2.205037,"eighty":-1.233979,"marketCap":31723804},{"date":"2021-12-23","current":-0.384856,"twenty":-4.246633,"median":-2.205037,"eighty":-1.233979,"marketCap":33294289},{"date":"2021-12-31","current":-0.331848,"twenty":-4.246633,"median":-2.205037,"eighty":-1.233979,"marketCap":28708472},{"date":"2022-01-07","current":-0.303637,"twenty":-4.23831,"median":-2.203543,"eighty":-1.231714,"marketCap":26267937},{"date":"2022-01-14","current":-0.284866,"twenty":-4.23831,"median":-2.203543,"eighty":-1.231714,"marketCap":24644056},{"date":"2022-01-21","current":-0.232366,"twenty":-4.23831,"median":-2.203543,"eighty":-1.231714,"marketCap":20102212},{"date":"2022-01-28","current":-0.200125,"twenty":-4.23831,"median":-2.203543,"eighty":-1.231714,"marketCap":17313030},{"date":"2022-02-04","current":-0.201832,"twenty":-4.23831,"median":-2.203543,"eighty":-1.231714,"marketCap":17460656},{"date":"2022-02-11","current":-0.189306,"twenty":-4.23831,"median":-2.203543,"eighty":-1.231714,"marketCap":16377021},{"date":"2022-02-18","current":-0.215955,"twenty":-4.23831,"median":-2.203543,"eighty":-1.231714,"marketCap":18682493},{"date":"2022-02-25","current":-0.217371,"twenty":-4.23831,"median":-2.203543,"eighty":-1.231714,"marketCap":18804991},{"date":"2022-03-04","current":-0.241552,"twenty":-4.23831,"median":-2.203543,"eighty":-1.231714,"marketCap":20896878},{"date":"2022-03-11","current":-0.236287,"twenty":-4.23831,"median":-2.203543,"eighty":-1.231714,"marketCap":20441437},{"date":"2022-03-18","current":-0.243403,"twenty":-4.23831,"median":-2.203543,"eighty":-1.231714,"marketCap":21057067},{"date":"2022-03-25","current":-0.248813,"twenty":-4.23831,"median":-2.203543,"eighty":-1.231714,"marketCap":21525072},{"date":"2022-04-01","current":-0.236294,"twenty":-4.23831,"median":-2.203543,"eighty":-1.231714,"marketCap":20778002},{"date":"2022-04-08","current":-0.219111,"twenty":-4.23831,"median":-2.203543,"eighty":-1.231714,"marketCap":19267104},{"date":"2022-04-14","current":-0.194197,"twenty":-4.23831,"median":-2.203543,"eighty":-1.231714,"marketCap":17076301},{"date":"2022-04-22","current":-0.20762,"twenty":-4.23831,"median":-2.203543,"eighty":-1.231714,"marketCap":18256690},{"date":"2022-04-29","current":-0.171466,"twenty":-4.23831,"median":-2.203543,"eighty":-1.225062,"marketCap":15077508},{"date":"2022-05-06","current":-0.175797,"twenty":-4.23831,"median":-2.203543,"eighty":-1.212181,"marketCap":15458380},{"date":"2022-05-13","current":-0.141671,"twenty":-4.23831,"median":-2.203543,"eighty":-1.209147,"marketCap":11338034},{"date":"2022-05-20","current":-0.149458,"twenty":-4.23831,"median":-2.203543,"eighty":-1.209147,"marketCap":11961280},{"date":"2022-05-27","current":-0.483772,"twenty":-4.23831,"median":-2.203543,"eighty":-1.209147,"marketCap":38716775},{"date":"2022-06-03","current":-0.491638,"twenty":-4.23831,"median":-2.203543,"eighty":-1.206318,"marketCap":39346316},{"date":"2022-06-10","current":-0.538836,"twenty":-4.23831,"median":-2.203543,"eighty":-1.206318,"marketCap":43123562},{"date":"2022-06-17","current":-0.570301,"twenty":-4.23831,"median":-2.203543,"eighty":-1.204728,"marketCap":45641726},{"date":"2022-06-24","current":-0.593899,"twenty":-4.246633,"median":-2.205037,"eighty":-1.203969,"marketCap":47530350},{"date":"2022-07-01","current":-0.704026,"twenty":-4.246633,"median":-2.205037,"eighty":-1.190642,"marketCap":56343924},{"date":"2022-07-08","current":-0.711892,"twenty":-4.246633,"median":-2.205037,"eighty":-1.183449,"marketCap":56973465},{"date":"2022-07-15","current":-0.688294,"twenty":-4.246633,"median":-2.205037,"eighty":-1.17379,"marketCap":55084842},{"date":"2022-07-22","current":-0.688294,"twenty":-4.246633,"median":-2.205037,"eighty":-1.166615,"marketCap":55084842},{"date":"2022-07-29","current":-0.688294,"twenty":-4.246633,"median":-2.205037,"eighty":-1.164065,"marketCap":55084842},{"date":"2022-08-05","current":-0.735491,"twenty":-4.246633,"median":-2.205037,"eighty":-1.164065,"marketCap":58862089},{"date":"2022-08-12","current":-0.755157,"twenty":-4.246633,"median":-2.205037,"eighty":-1.164065,"marketCap":60435941},{"date":"2022-08-19","current":-7.394562,"twenty":-4.319663,"median":-2.219417,"eighty":-1.173236,"marketCap":62639335},{"date":"2022-08-26","current":-6.948659,"twenty":-4.374472,"median":-2.231928,"eighty":-1.186522,"marketCap":58862089},{"date":"2022-09-02","current":-7.245928,"twenty":-4.467447,"median":-2.249855,"eighty":-1.198454,"marketCap":61380253},{"date":"2022-09-09","current":-7.245928,"twenty":-4.558156,"median":-2.284285,"eighty":-1.205949,"marketCap":61380253},{"date":"2022-09-16","current":-7.283086,"twenty":-4.607295,"median":-2.335818,"eighty":-1.223882,"marketCap":61695023},{"date":"2022-09-23","current":-1.818542,"twenty":-4.702259,"median":-2.339886,"eighty":-1.237407,"marketCap":15404869},{"date":"2022-09-30","current":-1.872794,"twenty":-4.702259,"median":-2.339886,"eighty":-1.24606,"marketCap":15864434},{"date":"2022-10-07","current":-1.9891,"twenty":-4.702259,"median":-2.339886,"eighty":-1.250381,"marketCap":16849666},{"date":"2022-10-14","current":-2.235462,"twenty":-4.702259,"median":-2.339886,"eighty":-1.264627,"marketCap":18936595},{"date":"2022-10-21","current":-2.143308,"twenty":-4.702259,"median":-2.339886,"eighty":-1.287061,"marketCap":18155964},{"date":"2022-10-28","current":-2.158172,"twenty":-4.702259,"median":-2.339886,"eighty":-1.31186,"marketCap":18281872},{"date":"2022-11-04","current":-2.07345,"twenty":-4.702259,"median":-2.339886,"eighty":-1.333243,"marketCap":17564195},{"date":"2022-11-11","current":-2.064904,"twenty":-4.702259,"median":-2.339886,"eighty":-1.341215,"marketCap":17491798},{"date":"2022-11-18","current":1.47314,"twenty":-4.702259,"median":-2.339886,"eighty":-1.340298,"marketCap":17505320},{"date":"2022-11-25","current":1.457505,"twenty":-4.702259,"median":-2.339886,"eighty":-1.333243,"marketCap":17319529},{"date":"2022-12-02","current":1.457505,"twenty":-4.702259,"median":-2.339886,"eighty":-1.31186,"marketCap":17319529},{"date":"2022-12-09","current":1.350444,"twenty":-4.702259,"median":-2.339886,"eighty":-1.287061,"marketCap":16047331},{"date":"2022-12-16","current":1.319704,"twenty":-4.702259,"median":-2.33949,"eighty":-1.264627,"marketCap":15682046},{"date":"2022-12-23","current":1.332954,"twenty":-4.702259,"median":-2.284285,"eighty":-1.246705,"marketCap":15839496},{"date":"2022-12-30","current":1.397879,"twenty":-4.702259,"median":-2.249855,"eighty":-1.238056,"marketCap":16611002},{"date":"2023-01-06","current":2.033511,"twenty":-4.702259,"median":-2.235462,"eighty":-1.228022,"marketCap":24164207},{"date":"2023-01-13","current":0.834057,"twenty":-4.702259,"median":-2.228683,"eighty":-1.205599,"marketCap":9911100},{"date":"2023-01-20","current":0.847084,"twenty":-4.603457,"median":-2.215921,"eighty":-1.195389,"marketCap":10065902},{"date":"2023-01-27","current":0.937321,"twenty":-4.472686,"median":-2.202049,"eighty":-1.178581,"marketCap":11138189},{"date":"2023-02-03","current":0.926201,"twenty":-4.288569,"median":-2.18711,"eighty":-1.155134,"marketCap":11006041},{"date":"2023-02-10","current":0.79434,"twenty":-4.214316,"median":-2.168359,"eighty":-1.126768,"marketCap":9439143},{"date":"2023-02-17","current":0.798471,"twenty":-4.189559,"median":-2.158428,"eighty":-0.733918,"marketCap":9488227},{"date":"2023-02-24","current":0.76352,"twenty":-4.166469,"median":-2.154549,"eighty":-0.722119,"marketCap":9072904},{"date":"2023-03-03","current":0.752081,"twenty":-4.104269,"median":-2.149915,"eighty":-0.702453,"marketCap":8936981},{"date":"2023-03-10","current":0.629435,"twenty":-4.033134,"median":-2.136015,"eighty":-0.69852,"marketCap":7479577},{"date":"2023-03-17","current":0.621492,"twenty":-4.001878,"median":-2.108214,"eighty":-0.69616,"marketCap":7385185},{"date":"2023-03-24","current":0.660891,"twenty":-3.965473,"median":-2.07345,"eighty":-0.690654,"marketCap":7853367},{"date":"2023-03-31","current":-0.948348,"twenty":-3.915415,"median":-2.065977,"eighty":-0.688294,"marketCap":7816283},{"date":"2023-04-06","current":-0.959343,"twenty":-3.889599,"median":-2.052815,"eighty":-0.688294,"marketCap":7906907},{"date":"2023-04-14","current":-1.006532,"twenty":-3.827716,"median":-2.025144,"eighty":-0.688294,"marketCap":8295833},{"date":"2023-04-21","current":-1.094952,"twenty":-3.800801,"median":-2.009658,"eighty":-0.688294,"marketCap":9024598},{"date":"2023-04-28","current":-1.035394,"twenty":-3.762866,"median":-1.990699,"eighty":-0.688294,"marketCap":8533720},{"date":"2023-05-05","current":-0.984999,"twenty":-3.721769,"median":-1.979984,"eighty":-0.688294,"marketCap":8118362},{"date":"2023-05-12","current":-1.034936,"twenty":-3.659217,"median":-1.959683,"eighty":-0.688294,"marketCap":8529944},{"date":"2023-05-19","current":1.307824,"twenty":-3.590813,"median":-1.953003,"eighty":-0.62356,"marketCap":8571480},{"date":"2023-05-26","current":1.269223,"twenty":-3.551824,"median":-1.941439,"eighty":-0.593899,"marketCap":8318489},{"date":"2023-06-02","current":1.225437,"twenty":-3.52457,"median":-1.933362,"eighty":-0.561113,"marketCap":8031514},{"date":"2023-06-09","current":1.293997,"twenty":-3.472925,"median":-1.931296,"eighty":-0.53097,"marketCap":8480856},{"date":"2023-06-16","current":1.429965,"twenty":-3.448626,"median":-1.923181,"eighty":-0.522991,"marketCap":9371988},{"date":"2023-06-23","current":1.832106,"twenty":-3.404905,"median":-1.909241,"eighty":-0.488682,"marketCap":12007624},{"date":"2023-06-30","current":1.947333,"twenty":-3.388492,"median":-1.894612,"eighty":-0.479372,"marketCap":12762820},{"date":"2023-07-07","current":1.958856,"twenty":-3.336284,"median":-1.890722,"eighty":-0.461086,"marketCap":12838340},{"date":"2023-07-14","current":2.017045,"twenty":-3.28054,"median":-1.87855,"eighty":-0.435864,"marketCap":13219714},{"date":"2023-07-21","current":2.369063,"twenty":-3.21113,"median":-1.860968,"eighty":-0.410271,"marketCap":15526840},{"date":"2023-07-28","current":2.082724,"twenty":-3.161463,"median":-1.848291,"eighty":-0.373238,"marketCap":13650176},{"date":"2023-08-04","current":2.074083,"twenty":-3.143393,"median":-1.84,"eighty":-0.35976,"marketCap":13593537},{"date":"2023-08-11","current":1.957703,"twenty":-3.125944,"median":-1.827398,"eighty":-0.343256,"marketCap":12830788},{"date":"2023-08-18","current":-0.381172,"twenty":-3.078872,"median":-1.818996,"eighty":-0.332284,"marketCap":18124716},{"date":"2023-08-25","current":-0.415288,"twenty":-3.029373,"median":-1.817905,"eighty":-0.332284,"marketCap":19746943},{"date":"2023-09-01","current":-0.446994,"twenty":-2.989657,"median":-1.810594,"eighty":-0.332284,"marketCap":21254547},{"date":"2023-09-08","current":-0.420639,"twenty":-2.973696,"median":-1.810594,"eighty":-0.332284,"marketCap":20001375},{"date":"2023-09-15","current":-0.445556,"twenty":-2.960128,"median":-1.795851,"eighty":-0.332284,"marketCap":21186192},{"date":"2023-09-22","current":-0.394524,"twenty":-2.933767,"median":-1.789589,"eighty":-0.332284,"marketCap":18759596},{"date":"2023-09-29","current":-0.391329,"twenty":-2.919659,"median":-1.782149,"eighty":-0.332284,"marketCap":18607697},{"date":"2023-10-06","current":-0.343411,"twenty":-2.899577,"median":-1.776987,"eighty":-0.332284,"marketCap":16329203},{"date":"2023-10-13","current":-0.327439,"twenty":-2.883682,"median":-1.764944,"eighty":-0.328321,"marketCap":15569705},{"date":"2023-10-20","current":-0.320251,"twenty":-2.87071,"median":-1.755982,"eighty":-0.319653,"marketCap":15227931},{"date":"2023-10-27","current":-0.430462,"twenty":-2.848433,"median":-1.751781,"eighty":-0.315974,"marketCap":20468466},{"date":"2025-06-17","current":-0.345681,"twenty":-2.587053,"median":-1.08579,"eighty":-0.175718,"marketCap":10192829},{"date":"2025-07-25","current":-2.530939,"twenty":-2.520186,"median":-0.984999,"eighty":-0.169604,"marketCap":180881157},{"date":"2025-08-01","current":-2.414306,"twenty":-2.512378,"median":-0.984999,"eighty":-0.169604,"marketCap":172545620},{"date":"2025-08-08","current":-2.138274,"twenty":-2.502835,"median":-0.984999,"eighty":-0.169604,"marketCap":152818182},{"date":"2025-08-15","current":-2.707833,"twenty":-2.507436,"median":-0.984999,"eighty":-0.169604,"marketCap":193523388},{"date":"2025-08-22","current":-3.939042,"twenty":-2.518451,"median":-0.984999,"eighty":-0.169604,"marketCap":281515449},{"date":"2025-08-29","current":-3.870656,"twenty":-2.533218,"median":-0.984999,"eighty":-0.169604,"marketCap":276628028},{"date":"2025-09-05","current":-3.744825,"twenty":-2.546538,"median":-0.982021,"eighty":-0.169461,"marketCap":267635173},{"date":"2025-09-12","current":-3.432984,"twenty":-2.56751,"median":-0.984999,"eighty":-0.169604,"marketCap":245348534},{"date":"2025-09-19","current":-3.539667,"twenty":-2.58242,"median":-0.984999,"eighty":-0.169604,"marketCap":252972910},{"date":"2025-09-26","current":-3.394688,"twenty":-2.593613,"median":-0.984999,"eighty":-0.169604,"marketCap":242611578},{"date":"2025-10-03","current":-3.290741,"twenty":-2.627618,"median":-0.984999,"eighty":-0.169604,"marketCap":235182698},{"date":"2025-10-10","current":-3.356392,"twenty":-2.661594,"median":-0.984999,"eighty":-0.169604,"marketCap":239874622},{"date":"2025-10-17","current":-3.378276,"twenty":-2.67655,"median":-0.984999,"eighty":-0.169604,"marketCap":241438597},{"date":"2025-10-24","current":-3.498635,"twenty":-2.689355,"median":-0.984999,"eighty":-0.169604,"marketCap":250040458},{"date":"2025-10-31","current":-3.422043,"twenty":-2.698677,"median":-0.984999,"eighty":-0.169604,"marketCap":244566546},{"date":"2025-11-07","current":-3.583434,"twenty":-2.742274,"median":-0.984999,"eighty":-0.169604,"marketCap":256100860},{"date":"2025-11-14","current":-3.5506,"twenty":-2.768258,"median":-0.984999,"eighty":-0.169604,"marketCap":253754301},{"date":"2025-11-21","current":-3.577955,"twenty":-2.801418,"median":-0.984999,"eighty":-0.169604,"marketCap":255709265},{"date":"2025-11-28","current":-4.116836,"twenty":-2.807709,"median":-0.984999,"eighty":-0.169604,"marketCap":294222051},{"date":"2025-12-05","current":-3.553336,"twenty":-2.825536,"median":-0.984999,"eighty":-0.169604,"marketCap":253949797},{"date":"2025-12-12","current":-4.187958,"twenty":-2.846705,"median":-0.984999,"eighty":-0.169604,"marketCap":299304957},{"date":"2025-12-19","current":-3.342707,"twenty":-2.846705,"median":-0.984999,"eighty":-0.169604,"marketCap":238896576},{"date":"2025-12-26","current":-3.383738,"twenty":-2.870518,"median":-0.984999,"eighty":-0.169604,"marketCap":241829022},{"date":"2026-01-02","current":-3.244231,"twenty":-2.887152,"median":-0.984999,"eighty":-0.169604,"marketCap":231858706},{"date":"2026-01-09","current":-3.000777,"twenty":-2.947456,"median":-0.984999,"eighty":-0.169604,"marketCap":214459528},{"date":"2026-01-16","current":-3.419299,"twenty":-2.997495,"median":-0.984999,"eighty":-0.169604,"marketCap":244370475},{"date":"2026-01-23","current":-3.728404,"twenty":-3.025943,"median":-0.984999,"eighty":-0.169604,"marketCap":266461565},{"date":"2026-01-30","current":-2.775103,"twenty":-3.025943,"median":-0.984999,"eighty":-0.169604,"marketCap":198331077},{"date":"2026-02-06","current":-2.574048,"twenty":-2.983248,"median":-0.984999,"eighty":-0.169604,"marketCap":183962093},{"date":"2026-02-13","current":-2.524811,"twenty":-2.910905,"median":-0.984999,"eighty":-0.169604,"marketCap":180443158},{"date":"2026-02-20","current":-3.211406,"twenty":-2.875674,"median":-0.984999,"eighty":-0.169604,"marketCap":229512750},{"date":"2026-02-27","current":-3.3769,"twenty":-2.875674,"median":-0.984999,"eighty":-0.169604,"marketCap":241340281},{"date":"2026-03-06","current":-2.444514,"twenty":-2.837274,"median":-0.984999,"eighty":-0.169604,"marketCap":376313362},{"date":"2026-03-13","current":-2.494138,"twenty":-2.807709,"median":-0.984999,"eighty":-0.169604,"marketCap":383952556},{"date":"2026-03-20","current":-2.291327,"twenty":-2.77895,"median":-0.984999,"eighty":-0.169604,"marketCap":352731501},{"date":"2026-03-27","current":-2.912704,"twenty":-2.749773,"median":-0.984999,"eighty":-0.169604,"marketCap":448387501},{"date":"2026-04-02","current":-4.168403,"twenty":-2.768258,"median":-0.984999,"eighty":-0.169604,"marketCap":641692335},{"date":"2026-04-10","current":-4.120937,"twenty":-2.768258,"median":-0.984999,"eighty":-0.169604,"marketCap":634385279},{"date":"2026-04-17","current":-4.196452,"twenty":-2.77895,"median":-0.984999,"eighty":-0.169604,"marketCap":646010141},{"date":"2026-04-24","current":-5.544926,"twenty":-2.829031,"median":-0.984999,"eighty":-0.169604,"marketCap":853596947},{"date":"2026-05-01","current":-4.828663,"twenty":-2.944974,"median":-0.984999,"eighty":-0.169604,"marketCap":743334005},{"date":"2026-05-08","current":-3.690363,"twenty":-3.025943,"median":-0.984999,"eighty":-0.169604,"marketCap":598123026},{"date":"2026-05-15","current":-4.352579,"twenty":-3.088318,"median":-0.984999,"eighty":-0.169604,"marketCap":705452880},{"date":"2026-05-22","current":-4.147558,"twenty":-3.181319,"median":-0.984999,"eighty":-0.169604,"marketCap":672223823},{"date":"2026-05-29","current":-4.401783,"twenty":-3.236025,"median":-0.982021,"eighty":-0.169461,"marketCap":713427853},{"date":"2026-06-05","current":-3.782622,"twenty":-3.282788,"median":-0.984999,"eighty":-0.169604,"marketCap":613076101},{"date":"2026-06-12","current":-3.76007,"twenty":-3.344356,"median":-0.984999,"eighty":-0.169604,"marketCap":609420905},{"date":"2026-06-18","current":-3.733418,"twenty":-3.377721,"median":-0.984999,"eighty":-0.169604,"marketCap":605101127},{"date":"2026-06-26","current":-3.483293,"twenty":-3.392498,"median":-0.982021,"eighty":-0.169461,"marketCap":564561678},{"date":"2026-07-02","current":-3.501745,"twenty":-3.405077,"median":-0.982021,"eighty":-0.169461,"marketCap":567552293},{"date":"2026-07-10","current":-3.436138,"twenty":-3.419305,"median":-0.982021,"eighty":-0.169461,"marketCap":556918995},{"date":"2026-07-17","current":-3.097855,"twenty":-3.419307,"median":-0.982021,"eighty":-0.169461,"marketCap":502091051},{"date":"2026-07-24","current":-4.342042,"twenty":-3.429702,"median":-0.982021,"eighty":-0.169461,"marketCap":703745165},{"date":"2026-07-31","current":-3.829564,"twenty":-3.446389,"median":-0.979043,"eighty":-0.169318,"marketCap":620684227},{"date":"2026-08-07","current":-4.258748,"twenty":-3.477142,"median":-0.979043,"eighty":-0.169318,"marketCap":703221448},{"date":"2026-08-14","current":-4.310589,"twenty":-3.491494,"median":-0.979043,"eighty":-0.169318,"marketCap":711781661},{"date":"2026-08-21","current":-4.206907,"twenty":-3.503795,"median":-0.979043,"eighty":-0.169318,"marketCap":694661236},{"date":"2026-08-28","current":-4.603491,"twenty":-3.542402,"median":-0.979043,"eighty":-0.169318,"marketCap":760146861},{"date":"2026-09-04","current":-5.287794,"twenty":-3.55505,"median":-0.979043,"eighty":-0.169318,"marketCap":873141664},{"date":"2026-09-10","current":-5.18152,"twenty":-3.55915,"median":-0.979043,"eighty":-0.169318,"marketCap":855593229}],"updateTime":1789117832743},"$inf$@#url:\"https://stock-news.skytigris.cn/v3/notice/important/events/list\",params:#symbol:\"CBIO\",pageSize:20,pageCount:5,market:\"us\",,,undefined,":[{"items":[{"cdn_pdf":false,"hasAttachments":true,"id":"15264782","market":"us","labels":[],"media":"sec.gov","original_id":"AN114036122027565-CBIO","pdf_url":"","pub_time":1659283200000,"showTitleType":true,"size":0,"source":"sec_us","summary":"8-K  - Current report","symbol":"CBIO","title":"8-K  - Current report","titleType":"Major Issues Report","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1124105/000114036122027565/0001140361-22-027565-index.htm","us_notice_code":"Form 8-K","us_title_en":"Item 8.01: Other Events;\nItem 9.01: Financial Statements and Exhibits","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"EXHIBIT 99.1","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000114036122027565/edge20002003x10_ex99-1.htm","primary":true,"translateUrl":"","linkName":"edge20002003x10_ex99-1.htm","type":"EX-99.1","id":"NTFILE9QYyzFHJ7VKN5pxB","market":"us","size":78101},{"description":"FORM 8-K","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000114036122027565/edge20002003x10_8k.htm","primary":false,"translateUrl":"","linkName":"edge20002003x10_8k.htm","type":"8-K","id":"NTFILE8ztHRn2Fony21Ue3","market":"us","size":26556},{"description":"EXHIBIT 99.2","seq":3,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000114036122027565/edge20002003x10_ex99-2.htm","primary":false,"translateUrl":"","linkName":"edge20002003x10_ex99-2.htm","type":"EX-99.2","id":"NTFILE2Nxjvi55prKUr2Lc","market":"us","size":13627}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Major Issues Report","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Major Issues Report","pubTime":"2022-08-01 00:00","pubTimestamp":1659283200,"title_zh":"8-K  - Current report","summary_en":"Item 8.01: Other Events;\nItem 9.01: Financial Statements and Exhibits","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"15264780","market":"us","labels":[],"media":"sec.gov","original_id":"AN110465922084700-CBIO","pdf_url":"","pub_time":1659283200000,"showTitleType":true,"size":0,"source":"sec_us","summary":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","symbol":"CBIO","title":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","titleType":"Beneficial Ownership Change","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1124105/000110465922084700/0001104659-22-084700-index.htm","us_notice_code":"Form SC 13D/A","us_title_en":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"SC 13D/A","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000110465922084700/tm2222229d1_sc13da.htm","primary":true,"translateUrl":"","linkName":"tm2222229d1_sc13da.htm","type":"SC 13D/A","id":"NTFILEGfJ7cLfGHVVyF6iU","market":"us","size":66600},{"description":"EXHIBIT 99.3","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000110465922084700/tm2222229d1_ex99-3.htm","primary":false,"translateUrl":"","linkName":"tm2222229d1_ex99-3.htm","type":"EX-99.3","id":"NTFILE3YZX57BzzRiC4Axk","market":"us","size":7080}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Beneficial Ownership Change","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Beneficial Ownership Change","pubTime":"2022-08-01 00:00","pubTimestamp":1659283200,"title_zh":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"15204914","market":"us","labels":[],"media":"sec.gov","original_id":"AN117152022000426-CBIO","pdf_url":"","pub_time":1658419200000,"showTitleType":true,"size":0,"source":"sec_us","summary":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","symbol":"CBIO","title":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","titleType":"Beneficial Ownership Change","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1124105/000117152022000426/0001171520-22-000426-index.htm","us_notice_code":"Form SC 13D/A","us_title_en":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000117152022000426/eps10375_jds.htm","primary":true,"translateUrl":"","linkName":"eps10375_jds.htm","type":"SC 13D/A","id":"NTFILEDdiUzeuVCd9opaHb","market":"us","size":177289}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Beneficial Ownership Change","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Beneficial Ownership Change","pubTime":"2022-07-22 00:00","pubTimestamp":1658419200,"title_zh":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"15175861","market":"us","labels":[],"media":"sec.gov","original_id":"AN114036122025671-CBIO","pdf_url":"","pub_time":1657468800000,"showTitleType":true,"size":0,"source":"sec_us","summary":"8-K  - Current report","symbol":"CBIO","title":"8-K  - Current report","titleType":"Major Issues Report","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1124105/000114036122025671/0001140361-22-025671-index.htm","us_notice_code":"Form 8-K","us_title_en":"Item 7.01: Regulation FD Disclosure;\nItem 9.01: Financial Statements and Exhibits","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"EXHIBIT 99.1","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000114036122025671/edge20002003x2_ex99-1.htm","primary":true,"translateUrl":"","linkName":"edge20002003x2_ex99-1.htm","type":"EX-99.1","id":"NTFILEBtRiLAepv9xZi9N8","market":"us","size":8409},{"description":"FORM 8-K","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000114036122025671/edge20002003x2_8k.htm","primary":false,"translateUrl":"","linkName":"edge20002003x2_8k.htm","type":"8-K","id":"NTFILEFTeEVfLmS2be1BJq","market":"us","size":26765},{"description":"","seq":6,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000114036122025671/edge20002003x2_ex99-1img01.jpg","primary":false,"translateUrl":"","linkName":"edge20002003x2_ex99-1img01.jpg","type":"GRAPHIC","id":"NTFILE3Lejz5FhGRXKtG4d","market":"us","size":1987826},{"description":"","seq":7,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000114036122025671/edge20002003x2_ex99-1img02.jpg","primary":false,"translateUrl":"","linkName":"edge20002003x2_ex99-1img02.jpg","type":"GRAPHIC","id":"NTFILE9AvsAc4N3xJvv4Cx","market":"us","size":960631},{"description":"","seq":8,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000114036122025671/edge20002003x2_ex99-1img03.jpg","primary":false,"translateUrl":"","linkName":"edge20002003x2_ex99-1img03.jpg","type":"GRAPHIC","id":"NTFILE56vbinLhbeh82PZk","market":"us","size":988709},{"description":"","seq":9,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000114036122025671/edge20002003x2_ex99-1img04.jpg","primary":false,"translateUrl":"","linkName":"edge20002003x2_ex99-1img04.jpg","type":"GRAPHIC","id":"NTFILEHoEXPUrwsgnAd5rp","market":"us","size":1911312},{"description":"","seq":10,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000114036122025671/edge20002003x2_ex99-1img05.jpg","primary":false,"translateUrl":"","linkName":"edge20002003x2_ex99-1img05.jpg","type":"GRAPHIC","id":"NTFILEG9XNideCKyED3a3m","market":"us","size":890282},{"description":"","seq":11,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000114036122025671/edge20002003x2_ex99-1img06.jpg","primary":false,"translateUrl":"","linkName":"edge20002003x2_ex99-1img06.jpg","type":"GRAPHIC","id":"NTFILEC9SLVJ7eWjAKoXTM","market":"us","size":1238307},{"description":"","seq":12,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000114036122025671/edge20002003x2_ex99-1img07.jpg","primary":false,"translateUrl":"","linkName":"edge20002003x2_ex99-1img07.jpg","type":"GRAPHIC","id":"NTFILEARepPdmS33FGZw13","market":"us","size":1179160},{"description":"","seq":13,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000114036122025671/edge20002003x2_ex99-1img08.jpg","primary":false,"translateUrl":"","linkName":"edge20002003x2_ex99-1img08.jpg","type":"GRAPHIC","id":"NTFILEBLSv2Z2rXYV6RtaH","market":"us","size":1305162},{"description":"","seq":14,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000114036122025671/edge20002003x2_ex99-1img09.jpg","primary":false,"translateUrl":"","linkName":"edge20002003x2_ex99-1img09.jpg","type":"GRAPHIC","id":"NTFILE91iXjjC88gurYgC2","market":"us","size":1208575},{"description":"","seq":15,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000114036122025671/edge20002003x2_ex99-1img10.jpg","primary":false,"translateUrl":"","linkName":"edge20002003x2_ex99-1img10.jpg","type":"GRAPHIC","id":"NTFILE8WArovjoQHmmyWfo","market":"us","size":971264},{"description":"","seq":16,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000114036122025671/edge20002003x2_ex99-1img11.jpg","primary":false,"translateUrl":"","linkName":"edge20002003x2_ex99-1img11.jpg","type":"GRAPHIC","id":"NTFILEEFuUYfJomHPYXmsw","market":"us","size":1580465},{"description":"","seq":17,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000114036122025671/edge20002003x2_ex99-1img12.jpg","primary":false,"translateUrl":"","linkName":"edge20002003x2_ex99-1img12.jpg","type":"GRAPHIC","id":"NTFILE3eV4D1Yd2HdUq6GD","market":"us","size":1550840},{"description":"","seq":18,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000114036122025671/edge20002003x2_ex99-1img13.jpg","primary":false,"translateUrl":"","linkName":"edge20002003x2_ex99-1img13.jpg","type":"GRAPHIC","id":"NTFILE4PsAPpt7Hu58Xm3H","market":"us","size":430148},{"description":"","seq":19,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000114036122025671/edge20002003x2_ex99-1img14.jpg","primary":false,"translateUrl":"","linkName":"edge20002003x2_ex99-1img14.jpg","type":"GRAPHIC","id":"NTFILE4Ch1seFw9QQCSX5r","market":"us","size":377198}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Major Issues Report","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Major Issues Report","pubTime":"2022-07-11 00:00","pubTimestamp":1657468800,"title_zh":"8-K  - Current report","summary_en":"Item 7.01: Regulation FD Disclosure;\nItem 9.01: Financial Statements and Exhibits","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"15109024","market":"us","labels":[],"media":"sec.gov","original_id":"AN110465922076841-CBIO","pdf_url":"","pub_time":1656604800000,"showTitleType":true,"size":0,"source":"sec_us","summary":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","symbol":"CBIO","title":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","titleType":"Beneficial Ownership Change","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1124105/000110465922076841/0001104659-22-076841-index.htm","us_notice_code":"Form SC 13D/A","us_title_en":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"SC 13D/A","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000110465922076841/tm2220246d1_sc13da.htm","primary":true,"translateUrl":"","linkName":"tm2220246d1_sc13da.htm","type":"SC 13D/A","id":"NTFILEGn7sMPTHPSmvXDkm","market":"us","size":71400},{"description":"EXHIBIT 99.2","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000110465922076841/tm2220246d1_ex99-2.htm","primary":false,"translateUrl":"","linkName":"tm2220246d1_ex99-2.htm","type":"EX-99.2","id":"NTFILEAUkk676L98Rtsft6","market":"us","size":4985}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Beneficial Ownership Change","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Beneficial Ownership Change","pubTime":"2022-07-01 00:00","pubTimestamp":1656604800,"title_zh":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"15109027","market":"us","labels":[],"media":"sec.gov","original_id":"AN119312522181696-CBIO","pdf_url":"","pub_time":1656259200000,"showTitleType":true,"size":0,"source":"sec_us","summary":"8-K  - Current report","symbol":"CBIO","title":"8-K  - Current report","titleType":"Major Issues Report","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522181696/0001193125-22-181696-index.htm","us_notice_code":"Form 8-K","us_title_en":"Item 8.01: Other Events;\nItem 9.01: Financial Statements and Exhibits","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"EX-99.1","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522181696/d387575dex991.htm","primary":true,"translateUrl":"","linkName":"d387575dex991.htm","type":"EX-99.1","id":"NTFILEEoaDvjz2kNTW7sV5","market":"us","size":210398},{"description":"8-K","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522181696/d387575d8k.htm","primary":false,"translateUrl":"","linkName":"d387575d8k.htm","type":"8-K","id":"NTFILE9eAhefUeNJ9GgZ51","market":"us","size":33225}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Major Issues Report","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Major Issues Report","pubTime":"2022-06-27 00:00","pubTimestamp":1656259200,"title_zh":"8-K  - Current report","summary_en":"Item 8.01: Other Events;\nItem 9.01: Financial Statements and Exhibits","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"15072804","market":"us","labels":[],"media":"sec.gov","original_id":"AN110465922073028-CBIO","pdf_url":"","pub_time":1655740800000,"showTitleType":true,"size":0,"source":"sec_us","summary":"SC 13D  - General statement of acquisition of beneficial ownership","symbol":"CBIO","title":"SC 13D  - General statement of acquisition of beneficial ownership","titleType":"Beneficial Ownership Change","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1124105/000110465922073028/0001104659-22-073028-index.htm","us_notice_code":"Form SC 13D","us_title_en":"SC 13D  - General statement of acquisition of beneficial ownership","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"SC 13D","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000110465922073028/tm2218945d1_sc13d.htm","primary":true,"translateUrl":"","linkName":"tm2218945d1_sc13d.htm","type":"SC 13D","id":"NTFILE9QtQLDA8c8JJZS7R","market":"us","size":99245},{"description":"EXHIBIT 99.1","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000110465922073028/tm2218945d1_ex99-1.htm","primary":false,"translateUrl":"","linkName":"tm2218945d1_ex99-1.htm","type":"EX-99.1","id":"NTFILEHSEmyyEJ5osFTcjD","market":"us","size":6752}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Beneficial Ownership Change","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Beneficial Ownership Change","pubTime":"2022-06-21 00:00","pubTimestamp":1655740800,"title_zh":"SC 13D  - General statement of acquisition of beneficial ownership","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"15038878","market":"us","labels":[],"media":"sec.gov","original_id":"AN117152022000371-CBIO","pdf_url":"","pub_time":1655395200000,"showTitleType":true,"size":0,"source":"sec_us","summary":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","symbol":"CBIO","title":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","titleType":"Beneficial Ownership Change","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1124105/000117152022000371/0001171520-22-000371-index.htm","us_notice_code":"Form SC 13D/A","us_title_en":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000117152022000371/eps10316.htm","primary":true,"translateUrl":"","linkName":"eps10316.htm","type":"SC 13D/A","id":"NTFILE8b7cf7ZmrcJ8PsEw","market":"us","size":148494}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Beneficial Ownership Change","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Beneficial Ownership Change","pubTime":"2022-06-17 00:00","pubTimestamp":1655395200,"title_zh":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"15005141","market":"us","labels":[],"media":"sec.gov","original_id":"AN119312522170374-CBIO","pdf_url":"","pub_time":1654704000000,"showTitleType":true,"size":0,"source":"sec_us","summary":"8-K  - Current report","symbol":"CBIO","title":"8-K  - Current report","titleType":"Major Issues Report","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522170374/0001193125-22-170374-index.htm","us_notice_code":"Form 8-K","us_title_en":"Item 8.01: Other Events","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"8-K","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522170374/d366052d8k.htm","primary":true,"translateUrl":"","linkName":"d366052d8k.htm","type":"8-K","id":"NTFILEBu67fRigzCvhY7H4","market":"us","size":26169}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Major Issues Report","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Major Issues Report","pubTime":"2022-06-09 00:00","pubTimestamp":1654704000,"title_zh":"8-K  - Current report","summary_en":"Item 8.01: Other Events","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"14935803","market":"us","labels":[],"media":"sec.gov","original_id":"AN117152022000347-CBIO","pdf_url":"","pub_time":1653408000000,"showTitleType":true,"size":0,"source":"sec_us","summary":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","symbol":"CBIO","title":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","titleType":"Beneficial Ownership Change","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1124105/000117152022000347/0001171520-22-000347-index.htm","us_notice_code":"Form SC 13D/A","us_title_en":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000117152022000347/eps10285.htm","primary":true,"translateUrl":"","linkName":"eps10285.htm","type":"SC 13D/A","id":"NTFILE2ZtXpXSjsau6Z6Kr","market":"us","size":182900}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Beneficial Ownership Change","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Beneficial Ownership Change","pubTime":"2022-05-25 00:00","pubTimestamp":1653408000,"title_zh":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"14935804","market":"us","labels":[],"media":"sec.gov","original_id":"AN119312522157739-CBIO","pdf_url":"","pub_time":1653321600000,"showTitleType":true,"size":0,"source":"sec_us","summary":"8-K/A [Amend]  - Current report","symbol":"CBIO","title":"8-K/A [Amend]  - Current report","titleType":"Major Issues Report","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522157739/0001193125-22-157739-index.htm","us_notice_code":"Form 8-K/A","us_title_en":"8-K/A [Amend]  - Current report","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"8-K/A","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522157739/d354796d8ka.htm","primary":true,"translateUrl":"","linkName":"d354796d8ka.htm","type":"8-K/A","id":"NTFILECiG7yiegM3ZwTMnM","market":"us","size":26634},{"description":"EX-99.2","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522157739/d354796dex992.htm","primary":false,"translateUrl":"","linkName":"d354796dex992.htm","type":"EX-99.2","id":"NTFILEpTNHfuDCVE1wpknR","market":"us","size":78745}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Major Issues Report","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Major Issues Report","pubTime":"2022-05-24 00:00","pubTimestamp":1653321600,"title_zh":"8-K/A [Amend]  - Current report","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"14909028","market":"us","labels":[],"media":"sec.gov","original_id":"AN119312522156879-CBIO","pdf_url":"","pub_time":1653235200000,"showTitleType":true,"size":0,"source":"sec_us","summary":"8-K  - Current report","symbol":"CBIO","title":"8-K  - Current report","titleType":"Major Issues Report","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522156879/0001193125-22-156879-index.htm","us_notice_code":"Form 8-K","us_title_en":"Item 1.01: Entry into a Material Definitive Agreement;\nItem 2.01: Completion of Acquisition or Disposition of Assets;\nItem 9.01: Financial Statements and Exhibits","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"EX-99.1","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522156879/d304590dex991.htm","primary":true,"translateUrl":"","linkName":"d304590dex991.htm","type":"EX-99.1","id":"NTFILEAMCvsaXSyvApYqkz","market":"us","size":95571},{"description":"8-K","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522156879/d304590d8k.htm","primary":false,"translateUrl":"","linkName":"d304590d8k.htm","type":"8-K","id":"NTFILEE6JxocTt54EM3eWt","market":"us","size":26814},{"description":"GRAPHIC","seq":6,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522156879/g304590dsp05.jpg","primary":false,"translateUrl":"","linkName":"g304590dsp05.jpg","type":"GRAPHIC","id":"NTFILE4eszhZe3TPuZ6rR9","market":"us","size":3929}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Major Issues Report","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Major Issues Report","pubTime":"2022-05-23 00:00","pubTimestamp":1653235200,"title_zh":"8-K  - Current report","summary_en":"Item 1.01: Entry into a Material Definitive Agreement;\nItem 2.01: Completion of Acquisition or Disposition of Assets;\nItem 9.01: Financial Statements and Exhibits","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"14854499","market":"us","labels":[],"media":"sec.gov","original_id":"AN117152022000299-CBIO","pdf_url":"","pub_time":1652112000000,"showTitleType":true,"size":0,"source":"sec_us","summary":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","symbol":"CBIO","title":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","titleType":"Beneficial Ownership Change","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1124105/000117152022000299/0001171520-22-000299-index.htm","us_notice_code":"Form SC 13D/A","us_title_en":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000117152022000299/eps10231.htm","primary":true,"translateUrl":"","linkName":"eps10231.htm","type":"SC 13D/A","id":"NTFILE9vnWaaKKDeNRUfF5","market":"us","size":148312}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Beneficial Ownership Change","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Beneficial Ownership Change","pubTime":"2022-05-10 00:00","pubTimestamp":1652112000,"title_zh":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"14854501","market":"us","labels":[],"media":"sec.gov","original_id":"AN119312522144986-CBIO","pdf_url":"","pub_time":1652025600000,"showTitleType":true,"size":0,"source":"sec_us","summary":"8-K  - Current report","symbol":"CBIO","title":"8-K  - Current report","titleType":"Major Issues Report","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522144986/0001193125-22-144986-index.htm","us_notice_code":"Form 8-K","us_title_en":"Item 2.02: Results of Operations and Financial Condition;\nItem 9.01: Financial Statements and Exhibits","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"EX-99.1","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522144986/d300508dex991.htm","primary":true,"translateUrl":"","linkName":"d300508dex991.htm","type":"EX-99.1","id":"NTFILE9KWGwytkbrEM3GK5","market":"us","size":54328},{"description":"8-K","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522144986/d300508d8k.htm","primary":false,"translateUrl":"","linkName":"d300508d8k.htm","type":"8-K","id":"NTFILE4aWBqpaYnNMAbXRt","market":"us","size":25899},{"description":"GRAPHIC","seq":6,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522144986/g300508g95s42.jpg","primary":false,"translateUrl":"","linkName":"g300508g95s42.jpg","type":"GRAPHIC","id":"NTFILE41LU6pTGnCF1tk3C","market":"us","size":9098}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Major Issues Report","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Major Issues Report","pubTime":"2022-05-09 00:00","pubTimestamp":1652025600,"title_zh":"8-K  - Current report","summary_en":"Item 2.02: Results of Operations and Financial Condition;\nItem 9.01: Financial Statements and Exhibits","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"14824735","market":"us","labels":[],"media":"sec.gov","original_id":"AN156459022018775-CBIO","pdf_url":"","pub_time":1652025600000,"showTitleType":true,"size":0,"source":"sec_us","summary":"10-Q  - Quarterly report [Sections 13 or 15(d)]","symbol":"CBIO","title":"10-Q  - Quarterly report [Sections 13 or 15(d)]","titleType":"Quarterly Report","type":"usFinancials","url":"https://www.sec.gov/Archives/edgar/data/1124105/000156459022018775/0001564590-22-018775-index.htm","us_notice_code":"Form 10-Q","us_title_en":"10-Q  - Quarterly report [Sections 13 or 15(d)]","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"10-Q","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000156459022018775/cbio-10q_20220331.htm","primary":true,"translateUrl":"","linkName":"cbio-10q_20220331.htm","type":"10-Q","id":"NTFILECT6GfQ9sy53CLuvX","market":"us","size":1297805},{"description":"EX-31.1","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000156459022018775/cbio-ex311_6.htm","primary":false,"translateUrl":"","linkName":"cbio-ex311_6.htm","type":"EX-31.1","id":"NTFILE9CwiNVGoNGpcW2Lb","market":"us","size":14280},{"description":"EX-31.2","seq":3,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000156459022018775/cbio-ex312_9.htm","primary":false,"translateUrl":"","linkName":"cbio-ex312_9.htm","type":"EX-31.2","id":"NTFILE9YznEQxyLgu4KmDY","market":"us","size":14287},{"description":"EX-32.1","seq":4,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000156459022018775/cbio-ex321_7.htm","primary":false,"translateUrl":"","linkName":"cbio-ex321_7.htm","type":"EX-32.1","id":"NTFILE5cV6pczoaTkEuvx2","market":"us","size":9778},{"description":"EX-32.2","seq":5,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000156459022018775/cbio-ex322_8.htm","primary":false,"translateUrl":"","linkName":"cbio-ex322_8.htm","type":"EX-32.2","id":"NTFILEDeiRAGzaBeuxMJXJ","market":"us","size":9784},{"description":"GRAPHIC","seq":6,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000156459022018775/gzuqpypd2gjn000001.jpg","primary":false,"translateUrl":"","linkName":"gzuqpypd2gjn000001.jpg","type":"GRAPHIC","id":"NTFILEDEM431PPcUv7nk6y","market":"us","size":498835}],"type_name":"Financial Report","type_name_en":"Financial Report","titleTypeEn":"Quarterly Report","us_type":"财务报告","us_type_zh":"财务报告","earn_infos":[],"event_type":"important_notice","event_name":"Quarterly Report","pubTime":"2022-05-09 00:00","pubTimestamp":1652025600,"title_zh":"10-Q  - Quarterly report [Sections 13 or 15(d","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"14784999","market":"us","labels":[],"media":"sec.gov","original_id":"AN117152022000271-CBIO","pdf_url":"","pub_time":1651420800000,"showTitleType":true,"size":0,"source":"sec_us","summary":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","symbol":"CBIO","title":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","titleType":"Beneficial Ownership Change","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1124105/000117152022000271/0001171520-22-000271-index.htm","us_notice_code":"Form SC 13D/A","us_title_en":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000117152022000271/eps10200.htm","primary":true,"translateUrl":"","linkName":"eps10200.htm","type":"SC 13D/A","id":"NTFILEE6YuhTwTu6VAWg1D","market":"us","size":145613}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Beneficial Ownership Change","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Beneficial Ownership Change","pubTime":"2022-05-02 00:00","pubTimestamp":1651420800,"title_zh":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"14784506","market":"us","labels":[],"media":"sec.gov","original_id":"AN119312522136435-CBIO","pdf_url":"","pub_time":1651420800000,"showTitleType":true,"size":0,"source":"sec_us","summary":"10-K/A [Amend]  - Annual report [Section 13 and 15(d), not S-K Item 405]","symbol":"CBIO","title":"10-K/A [Amend]  - Annual report [Section 13 and 15(d), not S-K Item 405]","titleType":"[Rev.]Annual Report","type":"usFinancials","url":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522136435/0001193125-22-136435-index.htm","us_notice_code":"Form 10-K/A","us_title_en":"10-K/A [Amend]  - Annual report [Section 13 and 15(d), not S-K Item 405]","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"FORM 10-K/A","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522136435/d212187d10ka.htm","primary":true,"translateUrl":"","linkName":"d212187d10ka.htm","type":"10-K/A","id":"NTFILECJZi3SPxMdNGMB73","market":"us","size":424161},{"description":"EX-31.03","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522136435/d212187dex3103.htm","primary":false,"translateUrl":"","linkName":"d212187dex3103.htm","type":"EX-31.03","id":"NTFILE7KHjnqfckpXkoYP7","market":"us","size":3230},{"description":"EX-31.04","seq":3,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522136435/d212187dex3104.htm","primary":false,"translateUrl":"","linkName":"d212187dex3104.htm","type":"EX-31.04","id":"NTFILECGUmeZ9nEu98P93c","market":"us","size":3242}],"type_name":"Financial Report","type_name_en":"Financial Report","titleTypeEn":"[Rev.]Annual Report","us_type":"财务报告","us_type_zh":"财务报告","earn_infos":[],"event_type":"important_notice","event_name":"[Rev.]Annual Report","pubTime":"2022-05-02 00:00","pubTimestamp":1651420800,"title_zh":"10-K/A [Amend]  - Annual report [Section 13 and 15(d), not S-K Item 405","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"14645699","market":"us","labels":[],"media":"sec.gov","original_id":"AN117152022000251-CBIO","pdf_url":"","pub_time":1650470400000,"showTitleType":true,"size":0,"source":"sec_us","summary":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","symbol":"CBIO","title":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","titleType":"Beneficial Ownership Change","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1124105/000117152022000251/0001171520-22-000251-index.htm","us_notice_code":"Form SC 13D/A","us_title_en":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000117152022000251/eps10184.htm","primary":true,"translateUrl":"","linkName":"eps10184.htm","type":"SC 13D/A","id":"NTFILE2PQx4Y4Pejvaruvf","market":"us","size":141739}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Beneficial Ownership Change","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Beneficial Ownership Change","pubTime":"2022-04-21 00:00","pubTimestamp":1650470400,"title_zh":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"14556807","market":"us","labels":[],"media":"sec.gov","original_id":"AN119312522095321-CBIO","pdf_url":"","pub_time":1649088000000,"showTitleType":true,"size":0,"source":"sec_us","summary":"8-K  - Current report","symbol":"CBIO","title":"8-K  - Current report","titleType":"Major Issues Report","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522095321/0001193125-22-095321-index.htm","us_notice_code":"Form 8-K","us_title_en":"Item 2.02: Results of Operations and Financial Condition;\nItem 2.05: Cost Associated with Exit or Disposal Activities;\nItem 5.02: Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers: Compensatory Arrangements of Certain Officers;\nItem 9.01: Financial Statements and Exhibits","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"EX-10.1","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522095321/d313223dex101.htm","primary":true,"translateUrl":"","linkName":"d313223dex101.htm","type":"EX-10.1","id":"NTFILEDEHW7S3yq1sm4M8w","market":"us","size":27543},{"description":"8-K","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522095321/d313223d8k.htm","primary":false,"translateUrl":"","linkName":"d313223d8k.htm","type":"8-K","id":"NTFILEGgPYXqLTLDQUvo1q","market":"us","size":33341},{"description":"EX-10.2","seq":3,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522095321/d313223dex102.htm","primary":false,"translateUrl":"","linkName":"d313223dex102.htm","type":"EX-10.2","id":"NTFILEGhxasT7NqpGTmxCA","market":"us","size":11275},{"description":"EX-99.1","seq":4,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522095321/d313223dex991.htm","primary":false,"translateUrl":"","linkName":"d313223dex991.htm","type":"EX-99.1","id":"NTFILE5jeAc1mk78EM3eSv","market":"us","size":58092},{"description":"GRAPHIC","seq":8,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522095321/g313223dsp001.jpg","primary":false,"translateUrl":"","linkName":"g313223dsp001.jpg","type":"GRAPHIC","id":"NTFILEHzb914A84rrShdfJ","market":"us","size":4231},{"description":"GRAPHIC","seq":9,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522095321/g313223g0405021300120.jpg","primary":false,"translateUrl":"","linkName":"g313223g0405021300120.jpg","type":"GRAPHIC","id":"NTFILE3XVgBQWTJVqaYiZ8","market":"us","size":8804}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Major Issues Report","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Major Issues Report","pubTime":"2022-04-05 00:00","pubTimestamp":1649088000,"title_zh":"8-K  - Current report","summary_en":"Item 2.02: Results of Operations and Financial Condition;\nItem 2.05: Cost Associated with Exit or Disposal Activities;\nItem 5.02: Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers: Compensatory Arrangements of Certain Officers;\nItem 9.01: Financial Statements and Exhibits","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"14517465","market":"us","labels":[],"media":"sec.gov","original_id":"AN156459022012877-CBIO","pdf_url":"","pub_time":1648656000000,"showTitleType":true,"size":0,"source":"sec_us","summary":"10-K  - Annual report [Section 13 and 15(d), not S-K Item 405]","symbol":"CBIO","title":"10-K  - Annual report [Section 13 and 15(d), not S-K Item 405]","titleType":"Annual Report","type":"usFinancials","url":"https://www.sec.gov/Archives/edgar/data/1124105/000156459022012877/0001564590-22-012877-index.htm","us_notice_code":"Form 10-K","us_title_en":"10-K  - Annual report [Section 13 and 15(d), not S-K Item 405]","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"10-K","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000156459022012877/cbio-10k_20211231.htm","primary":true,"translateUrl":"","linkName":"cbio-10k_20211231.htm","type":"10-K","id":"NTFILECB4L9n75hhRE9SHi","market":"us","size":2732531},{"description":"EX-10.8","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000156459022012877/cbio-ex108_9.htm","primary":false,"translateUrl":"","linkName":"cbio-ex108_9.htm","type":"EX-10.8","id":"NTFILEGBb7ypNE2vXMitsD","market":"us","size":72186},{"description":"EX-23.1","seq":3,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000156459022012877/cbio-ex231_8.htm","primary":false,"translateUrl":"","linkName":"cbio-ex231_8.htm","type":"EX-23.1","id":"NTFILE64EGve9vsXgGYw94","market":"us","size":3867},{"description":"EX-31.1","seq":4,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000156459022012877/cbio-ex311_11.htm","primary":false,"translateUrl":"","linkName":"cbio-ex311_11.htm","type":"EX-31.1","id":"NTFILE5tbvhjHHmd1tfT4d","market":"us","size":17802},{"description":"EX-31.2","seq":5,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000156459022012877/cbio-ex312_6.htm","primary":false,"translateUrl":"","linkName":"cbio-ex312_6.htm","type":"EX-31.2","id":"NTFILEGGerxbBw59ZedhKj","market":"us","size":17690},{"description":"EX-32.1","seq":6,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000156459022012877/cbio-ex321_7.htm","primary":false,"translateUrl":"","linkName":"cbio-ex321_7.htm","type":"EX-32.1","id":"NTFILECzAUNPeK2udRCcoE","market":"us","size":5338},{"description":"EX-32.2","seq":7,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000156459022012877/cbio-ex322_10.htm","primary":false,"translateUrl":"","linkName":"cbio-ex322_10.htm","type":"EX-32.2","id":"NTFILECS4MtedtEZzqMiPM","market":"us","size":5279},{"description":"GRAPHIC","seq":8,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000156459022012877/guycyz0ib1ig000001.jpg","primary":false,"translateUrl":"","linkName":"guycyz0ib1ig000001.jpg","type":"GRAPHIC","id":"NTFILEG4o1SaG7iSudFgmS","market":"us","size":130550},{"description":"GRAPHIC","seq":9,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000156459022012877/guycyz0ib1ig000002.jpg","primary":false,"translateUrl":"","linkName":"guycyz0ib1ig000002.jpg","type":"GRAPHIC","id":"NTFILE28AP3hsTgeYu2613","market":"us","size":238619},{"description":"GRAPHIC","seq":10,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000156459022012877/guycyz0ib1ig000003.jpg","primary":false,"translateUrl":"","linkName":"guycyz0ib1ig000003.jpg","type":"GRAPHIC","id":"NTFILEGewBFtrnzqGYaDcC","market":"us","size":130550}],"type_name":"Financial Report","type_name_en":"Financial Report","titleTypeEn":"Annual Report","us_type":"财务报告","us_type_zh":"财务报告","earn_infos":[],"event_type":"important_notice","event_name":"Annual Report","pubTime":"2022-03-31 00:00","pubTimestamp":1648656000,"title_zh":"10-K  - Annual report [Section 13 and 15(d), not S-K Item 405","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0}],"pageSize":20,"totalPage":14,"pageCount":5,"totalSize":268,"code":"91000000","status":"200"}]}}