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Ionis Pharmaceuticals

55.11

-0.5450-0.98%

Volume:999.90K

Turnover:55.24M

Market Cap:9.16B

PE:-15.83

High:56.15

Open:55.71

Low:54.81

Close:55.65

52wk High:86.74

52wk Low:50.01

Shares:166.18M

Float Shares:161.92M

Volume Ratio:0.29

T/O Rate:0.62%

Dividend:- -

Dividend Rate:- -

EPS(TTM):-3.4800

EPS(LYR):-2.3812

ROE:-105.50%

ROA:-12.42%

PB:20.83

PE(LYR):-23.14

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Overview Company News Filings

Ionis director Spencer R. Berthelsen disposes of 8,000 common shares for $605,360

Ionis Pharmaceuticals Price Target Maintained With a $125.00/Share by HC Wainwright & Co.

Ionis Pharmaceuticals: Advancing Pipeline, HBV Phase III Success, and Robust Catalyst Flow Underpin Buy Rating

Ionis partner GSK reports B-Well 1, B-Well 2 trials meet primary endpoint

Ionis Partner GSK Announces Bepirovirsen Achieves Unprecedented Functional Cure Rates With Potential to Redefine Treatment for Chronic Hepatitis B

THOMSON REUTERS

A New, Powerful Cholesterol-Lowering Drug Is on the Horizon -- WSJ

U.S. RESEARCH ROUNDUP-CAVA Group, Eagle Materials, Vertiv

J.P. Morgan Sticks to Their Buy Rating for Ionis Pharmaceuticals (IONS)

Ionis Pharmaceuticals Initiated at Buy by Citigroup

Ionis Pharmaceuticals initiated with a Buy, named a top pick at Citi

Assessing Ionis Pharmaceuticals (IONS) Valuation As Shares Cool After A Multi Year Run

Simply Wall St.

Ionis CEO Brett P. Monia disposes of USD 361,478 common shares

Ionis Pharmaceuticals participates in a conference call with Cantor

BRIEF-Ionis Partner Biogen Announces Topline Results From Phase 2 Celia Study Of Diranersen

Ionis Partner Biogen Announces Topline Results From Phase 2 Celia Study of Diranersen (Biib080): First Study to Show Reduction in Tau Pathology and Cognitive Benefit in Patients With Early Alzheimer’s Disease

THOMSON REUTERS

Ionis director Joseph Loscalzo disposes of common shares worth $5.8 million

Ionis director Joseph Klein III disposes of common shares worth $742,586.86

Ionis Pharmaceuticals announces virtual annual shareholder meeting

A Look At Ionis Pharmaceuticals (IONS) Valuation After FDA Priority Review Wins And Upgraded Revenue Guidance

Simply Wall St.

Ionis to present at Bank of America health care conference fireside chat

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director Spencer R. Berthelsen disposes of 8,000 common shares for $605,360","url":"https://stock-news.laohu8.com/highlight/detail?id=2640182914","media":"Reuters","labels":["shareholding","insiderTrades"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2640182914?lang=en_us&edition=fundamental","pubTime":"2026-06-04 05:35","pubTimestamp":1780522507,"startTime":"0","endTime":"0","summary":"Ionis Pharmaceuticals director Spencer R. Berthelsen exercised options to buy 8,000 shares at USD 24.42 on June 1.He sold 8,000 shares at USD 75.67 the same day.He reported 156,013 shares owned directly following the transactions.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Ionis Pharmaceuticals Inc. published the original content used to generate this news brief via EDGAR, the Electronic Data Gathering, Analysis, and Retrieval system operated by the U.S. Securities and Exchange Commission , on June 03, 2026, and is solely responsible for the information contained therein.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260603:nNDLcqJ57:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":"Ionis director Spencer R. Berthelsen disposes of 8,000 common shares for $605,360","news_tag":"shareholding,insiderTrades","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2640995931","title":"Ionis Pharmaceuticals Price Target Maintained With a $125.00/Share by HC Wainwright & Co.","url":"https://stock-news.laohu8.com/highlight/detail?id=2640995931","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2640995931?lang=en_us&edition=fundamental","pubTime":"2026-06-01 19:45","pubTimestamp":1780314300,"startTime":"0","endTime":"0","summary":"Ratings actions from Benzinga: https://www.benzinga.com/quote/IONS/analyst-ratings \n\n\n \n\n\n  (END) Dow Jones Newswires\n\n\n  June 01, 2026 07:45 ET (11:45 GMT)","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2639692011","title":"Ionis Pharmaceuticals: Advancing Pipeline, HBV Phase III Success, and Robust Catalyst Flow Underpin Buy Rating","url":"https://stock-news.laohu8.com/highlight/detail?id=2639692011","media":"TIPRANKS","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2639692011?lang=en_us&edition=fundamental","pubTime":"2026-05-28 23:45","pubTimestamp":1779983121,"startTime":"0","endTime":"0","summary":"William Blair analyst Myles Minter has reiterated their bullish stance on IONS stock, giving a Buy rating today. Myles Minter has given his Buy rat...","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/ratings/ionis-pharmaceuticals-advancing-pipeline-hbv-phase-iii-success-and-robust-catalyst-flow-underpin-buy-rating-ratings-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/ratings/ionis-pharmaceuticals-advancing-pipeline-hbv-phase-iii-success-and-robust-catalyst-flow-underpin-buy-rating-ratings-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["IONS","III"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2638696556","title":"Ionis partner GSK reports B-Well 1, B-Well 2 trials meet primary endpoint","url":"https://stock-news.laohu8.com/highlight/detail?id=2638696556","media":"TIPRANKS","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2638696556?lang=en_us&edition=fundamental","pubTime":"2026-05-28 17:21","pubTimestamp":1779960078,"startTime":"0","endTime":"0","summary":"Ionis Pharmaceuticals (IONS) partner GSK (GSK) announced data for bepirovirsen, an investigational antisense oligonucleotide for the treatment of c...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/ionis-partner-gsk-reports-b-well-1-b-well-2-trials-meet-primary-endpoint-thefly-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/ionis-partner-gsk-reports-b-well-1-b-well-2-trials-meet-primary-endpoint-thefly-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4139","LU1829250122.USD","BK4532","BK4585","IONS","BK4007","BK4588","GSK.UK","GSK","GSKH"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2638666828","title":"Ionis Partner GSK Announces Bepirovirsen Achieves Unprecedented Functional Cure Rates With Potential to Redefine Treatment for Chronic Hepatitis B","url":"https://stock-news.laohu8.com/highlight/detail?id=2638666828","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2638666828?lang=en_us&edition=fundamental","pubTime":"2026-05-28 16:45","pubTimestamp":1779957902,"startTime":"0","endTime":"0","summary":null,"market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260528:nTUA1MND9V:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2638684413","title":"A New, Powerful Cholesterol-Lowering Drug Is on the Horizon -- WSJ","url":"https://stock-news.laohu8.com/highlight/detail?id=2638684413","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2638684413?lang=en_us&edition=fundamental","pubTime":"2026-05-28 00:00","pubTimestamp":1779897600,"startTime":"0","endTime":"0","summary":"A new class of drugs is poised to take on an insidious cause of heart attacks and strokes that has eluded treatment for decades.Amgen and Eli Lilly are also developing medicines that lower the level of lipoprotein, a fatty particle in the blood that is known as Lp. It can cause plaque to build up in blood vessels and is linked to heart disease.Tens of millions of people in the U.S. have elevated Lp, an inherited and largely hidden driver of heart disease. If Lp drugs work, companies could be on the verge of the next big heart-drug market. Citi analysts estimate it could be valued at as much as $25 billion a year worldwide.This isn't a sure bet, though. Effective Lp drugs have proven difficult to develop. In the past, scientists found drugs that lowered levels of the particle a moderate amount but failed to reduce heart attacks and strokes in research studies, leaving patients with no approved treatment.","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU0787776722.HKD","LU0320765992.SGD","LU2491049909.HKD","IE00B4JS1V06.HKD","SG9999014914.USD","LU2237443549.SGD","SG9999018865.SGD","LU2471134796.USD","SGXZ81514606.USD","LU0889565916.HKD","IE0004445239.USD","LU1868836757.USD","SGXZ57979304.SGD","BK4585","LU0689472784.USD","LU2417539215.USD","SG9999014898.SGD","SG9999015986.USD","LU0882574139.USD","BK4139","LU1989771016.USD","LU2456880835.USD","SG9999017495.SGD","IE00BKPKM429.USD","LU1983299246.USD","LU2108987350.USD","GB00BDT5M118.USD","SG9999015978.USD","LU2265009873.SGD","LU2237438978.USD","LU2264538146.SGD","LU2089284900.SGD","LU1023059063.AUD","LU2237443382.USD","LU0385154629.USD","LU1814569148.SGD","LU0238689110.USD","LU2471134523.USD","IONS","LU0234572021.USD","LU0122379950.USD","LU0203201768.USD","BK4007","LU1571399168.USD","LU2750360997.AUD","SG9999001176.USD","LLII","LU2168564065.EUR","BK4599","LU1974910355.USD","LU2168563687.JPY","LU0208291251.USD","BK4588","LU2236285917.USD","LU1988902786.USD","LU0114720955.EUR","IE00BJLML261.HKD","LU0417517546.SGD","BK4533","LU1720051017.SGD","LU0109391861.USD","LU1366192091.USD","LU2602419157.SGD","IE00BK4W5M84.HKD","LU2087625088.SGD","IE0002141913.USD","LU1035775433.USD","LU1712237335.SGD","AMGN","LU2023250504.SGD","LU0106261372.USD","LU2213496289.HKD","ELIL","LU0354030511.USD","IE00B7KXQ091.USD","SG9999001176.SGD","IE00BJT1NW94.SGD","LU1069344957.HKD","LU0456855351.SGD","SG9999015952.SGD","LU1629891620.HKD","LU2242646821.SGD","LU2089984988.USD","LU0820561818.USD","LU0466842654.USD","LU1291159041.SGD","ELIS","LU0432979614.USD","SGXZ31699556.SGD","LU0203202063.USD","LU0211331839.USD","LU0823416689.USD","NVS","LU1623119135.USD","LU2746668461.USD","IE00BFTCPJ56.SGD","LU2756315664.SGD","LU1720051108.HKD","BK4532","LU0094547139.USD","LU2112291526.USD","SG9999018857.SGD","LU0786609619.USD","LU2491050071.SGD","LU0289739699.SGD","LU2168564495.EUR","LU0353189680.USD","LU2361044865.SGD","LU2028103732.USD","LU0882574055.USD","LU0683600562.USD","LU0058720904.USD","LU2242652126.USD","SG9999001440.SGD","BK4578","04332","IE00BWXC8680.SGD","LU0225283273.USD","LU0820561909.HKD","LU2211815571.USD","LU2360106947.USD","LU0256863811.USD","LU2462157665.USD","SG9999013999.USD","LU0158827948.USD","IE00BFSS8Q28.SGD","LU0672654240.SGD","LU0320765059.SGD","LU1551013342.USD","LU0323591593.USD","LU0471298694.HKD","LU2237443622.USD","LU2552382132.HKD","SGXZ51526630.SGD","LU1093756325.SGD","LU1551013425.SGD","IE00B775H168.HKD","IE00BJJMRX11.SGD","BK4566","LU2106854487.HKD","LU2361045086.USD","SG9999015945.SGD","LU0471298777.SGD","LU2552382058.USD","LU0320765489.SGD","SGXZ99366536.SGD","LU0820562030.AUD","LU2063271972.USD","LU0708995401.HKD","LU0868494617.USD","LU2237443465.HKD","LU1057294990.SGD","IE0004445015.USD","IE00BN29S564.USD","LU0061475181.USD","IE0001KFT4U8.USD","LU0097036916.USD","LU1145028129.USD","IE00B2B36J28.USD","LU0354030438.USD","LU0210536198.USD","LU1804176565.USD","LU2896262040.SGD","LU0070302665.USD","LU2357305700.SGD","LU2461242641.AUD","LU2471134952.CNY","LLYZ","LU0823434740.USD","LU2471134879.HKD","LU0943347566.SGD","LU2168564149.EUR","LU2491050154.USD","LU2111349929.HKD","LU1280957306.USD","LU1917777945.USD","BK4516","LU2271345857.HKD","LU1093756168.USD","LU2023251221.USD","LU0006306889.USD","LU2237443895.HKD","IE00B1BXHZ80.USD","LLY","BK4581","LU2756315318.SGD","LU0079474960.USD","IE00BFSS7M15.SGD","LU0109394709.USD","LU0823434583.USD","LU1267930730.SGD","LU2023250330.USD","LU2168564222.USD","IE00BKDWB100.SGD","LU1127390331.HKD","LU0266013472.USD","LU0316494557.USD","LU2746668974.SGD","IE00B4R5TH58.HKD","LU1868836914.USD","IE00B1XK9C88.USD","LU1064131342.USD","SG9999014880.SGD","LLYX","LU0256863902.USD","IE00BJJMRY28.SGD","LU1323610961.USD","LU2750360641.GBP","LU2324357040.USD","IE00BK4W5L77.USD","LU2237443978.SGD","LU1061106388.HKD","IE0009355771.USD","LU0096364046.USD","LU1868837136.USD","LU1868837300.USD","SG9999014906.USD","LU0964807845.USD","LU2361044949.HKD","IE0005OL40V9.USD","LU0198837287.USD","LU2468319806.SGD","LU0133085943.USD","LU1868836591.USD","LU2552382215.SGD","LU0158827781.USD","LU0353189763.USD","LU0640476718.USD","LU1232071149.USD","BK4534","IE00BJJMRZ35.SGD","LU2089283258.USD","LU1548497426.USD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2636162018","title":"U.S. RESEARCH ROUNDUP-CAVA Group, Eagle Materials, Vertiv","url":"https://stock-news.laohu8.com/highlight/detail?id=2636162018","media":"Reuters","labels":["shareholding"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2636162018?lang=en_us&edition=fundamental","pubTime":"2026-05-20 15:07","pubTimestamp":1779260842,"startTime":"0","endTime":"0","summary":"U.S. RESEARCH ROUNDUP-CAVA Group, Eagle Materials, VertivMay 20 (Reuters) - Wall Street securities analysts revised their ratings and price targets on several U.S.-listed companies, including CAVA Gro","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260520:nL4N41X0MK:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"shareholding","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LRCX","GGLL","CHRW","INCY","CRC","DVN","CAVA","JAZZ","META","GGLS","CRWD","HALO","IONS","USAW.SI","AMZD","KEYS","CRWL","S","FANG","BMRN","HD","HUM","BRO","LMRI","AMRX","AMZY","DRUG","APA","DKS","KLAC","HSY","MRVL","CVS","CNC","EBAY","WHD","GOOGL","EXP","LRCU","MIRM","ELV","ALNY","CNCG","MRVU","AMZN","INSM","EOG","MVLL","AMZU"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2636657948","title":"J.P. Morgan Sticks to Their Buy Rating for Ionis Pharmaceuticals (IONS)","url":"https://stock-news.laohu8.com/highlight/detail?id=2636657948","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2636657948?lang=en_us&edition=fundamental","pubTime":"2026-05-20 01:55","pubTimestamp":1779213325,"startTime":"0","endTime":"0","summary":"In a report released today, Eric Joseph from J.P. Morgan maintained a Buy rating on Ionis Pharmaceuticals, with a price target of $115.00. Accordin...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/j-p-morgan-sticks-to-their-buy-rating-for-ionis-pharmaceuticals-ions-blurbs-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/j-p-morgan-sticks-to-their-buy-rating-for-ionis-pharmaceuticals-ions-blurbs-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2636857341","title":"Ionis Pharmaceuticals Initiated at Buy by Citigroup","url":"https://stock-news.laohu8.com/highlight/detail?id=2636857341","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2636857341?lang=en_us&edition=fundamental","pubTime":"2026-05-19 22:37","pubTimestamp":1779201420,"startTime":"0","endTime":"0","summary":"Ratings actions from Benzinga: https://www.benzinga.com/quote/IONS/analyst-ratings \n\n\n \n\n\n  (END) Dow Jones Newswires\n\n\n  May 19, 2026 10:37 ET (14:37 GMT)","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2636009293","title":"Ionis Pharmaceuticals initiated with a Buy, named a top pick at Citi","url":"https://stock-news.laohu8.com/highlight/detail?id=2636009293","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2636009293?lang=en_us&edition=fundamental","pubTime":"2026-05-19 04:21","pubTimestamp":1779135661,"startTime":"0","endTime":"0","summary":"Citi initiated coverage of Ionis Pharmaceuticals (IONS) with a Buy rating and $115 price target and named it a top pick among small-to-mid cap biot...","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/ionis-pharmaceuticals-initiated-with-a-buy-named-a-top-pick-at-citi-thefly-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/ionis-pharmaceuticals-initiated-with-a-buy-named-a-top-pick-at-citi-thefly-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4139","IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2635506673","title":"Assessing Ionis Pharmaceuticals (IONS) Valuation As Shares Cool After A Multi Year Run","url":"https://stock-news.laohu8.com/highlight/detail?id=2635506673","media":"Simply Wall St.","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2635506673?lang=en_us&edition=fundamental","pubTime":"2026-05-16 23:33","pubTimestamp":1778945608,"startTime":"0","endTime":"0","summary":"Recent stock performance and context\nIonis Pharmaceuticals (IONS) has seen its stock give back some ground recently, with the price down about 2% over the past week and roughly 1% over the past month, against a 7% decline over the past 3 months.\nSee our latest analysis for Ionis Pharmaceuticals.\nZooming out, Ionis Pharmaceuticals’ share price has cooled recently. However, its 1-year total shareholder return of 121.19% and 3-year total shareholder return of 89.41% indicate that longer term...","market":"nz","thumbnail":"https://images.simplywall.st/asset/industry/6111000-choice2-main-header/1585186599552","type":0,"news_type":0,"thumbnails":["https://images.simplywall.st/asset/industry/6111000-choice2-main-header/1585186599552"],"rights":{"source":"simplywall_highlight","url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-ions/ionis-pharmaceuticals/news/assessing-ionis-pharmaceuticals-ions-valuation-as-shares-coo","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-ions/ionis-pharmaceuticals/news/assessing-ionis-pharmaceuticals-ions-valuation-as-shares-coo","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"simplywall_highlight","symbols":["IONS","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2635558360","title":"Ionis CEO Brett P. Monia disposes of USD 361,478 common shares","url":"https://stock-news.laohu8.com/highlight/detail?id=2635558360","media":"Reuters","labels":["shareholding","insiderTrades"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2635558360?lang=en_us&edition=fundamental","pubTime":"2026-05-16 06:15","pubTimestamp":1778883355,"startTime":"0","endTime":"0","summary":"Ionis Pharmaceuticals CEO and director Brett P. Monia sold 4,536 shares of common stock in transactions dated May 13-14.Sales were executed at weighted average prices of $78.01 and $78.68.Monia acquired 4,536 shares via option exercises at $32.6 per share.Directly held common stock position stood at 242,662 shares after the transactions.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Ionis Pharmaceuticals Inc. published the original content used to generate this news brief via EDGAR, the Electronic Data Gathering, Analysis, and Retrieval system operated by the U.S. Securities and Exchange Commission , on May 15, 2026, and is solely responsible for the information contained therein.","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260515:nNDL15zFYY:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":"Ionis CEO Brett P. Monia disposes of USD 361,478 common shares","news_tag":"shareholding,insiderTrades","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2635726157","title":"Ionis Pharmaceuticals participates in a conference call with Cantor","url":"https://stock-news.laohu8.com/highlight/detail?id=2635726157","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2635726157?lang=en_us&edition=fundamental","pubTime":"2026-05-15 04:35","pubTimestamp":1778790925,"startTime":"0","endTime":"0","summary":"Conference call with management will be held on May 15 at 11 am hosted by Cantor.Webcast Link Published first on TheFly – the ultimate source for r...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/ionis-pharmaceuticals-participates-in-a-conference-call-with-cantor-thefly-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/ionis-pharmaceuticals-participates-in-a-conference-call-with-cantor-thefly-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4139","IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2635719405","title":"BRIEF-Ionis Partner Biogen Announces Topline Results From Phase 2 Celia Study Of Diranersen","url":"https://stock-news.laohu8.com/highlight/detail?id=2635719405","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2635719405?lang=en_us&edition=fundamental","pubTime":"2026-05-14 19:05","pubTimestamp":1778756754,"startTime":"0","endTime":"0","summary":"BRIEF-Ionis Partner Biogen Announces Topline Results From Phase 2 Celia Study Of Diranersen May 14 (Reuters) - Ionis Pharmaceuticals Inc IONS.O:IONIS PARTNER BIOGEN ANNOUNCES TOPLINE RESULTS FROM PHAS","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260514:nTUA7VV3V8:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2635410719","title":"Ionis Partner Biogen Announces Topline Results From Phase 2 Celia Study of Diranersen (Biib080): First Study to Show Reduction in Tau Pathology and Cognitive Benefit in Patients With Early Alzheimer’s Disease","url":"https://stock-news.laohu8.com/highlight/detail?id=2635410719","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2635410719?lang=en_us&edition=fundamental","pubTime":"2026-05-14 19:05","pubTimestamp":1778756700,"startTime":"0","endTime":"0","summary":null,"market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260514:nTUA7VV3V8:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["IONS","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2633632091","title":"Ionis director Joseph Loscalzo disposes of common shares worth $5.8 million","url":"https://stock-news.laohu8.com/highlight/detail?id=2633632091","media":"Reuters","labels":["shareholding","insiderTrades"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2633632091?lang=en_us&edition=fundamental","pubTime":"2026-05-07 06:13","pubTimestamp":1778105616,"startTime":"0","endTime":"0","summary":"Ionis Pharmaceuticals director Joseph Loscalzo sold 77,289 shares of common stock on May 4, 2026 at weighted average prices of $74.9 and $75.58.He also exercised stock options for 77,289 shares at prices ranging from $38.06 to $64.8.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Ionis Pharmaceuticals Inc. published the original content used to generate this news brief via EDGAR, the Electronic Data Gathering, Analysis, and Retrieval system operated by the U.S. Securities and Exchange Commission , on May 06, 2026, and is solely responsible for the information contained therein.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260506:nNDL4YtgS3:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":"Ionis director Joseph Loscalzo disposes of common shares worth $5.8 million","news_tag":"shareholding,insiderTrades","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2633924533","title":"Ionis director Joseph Klein III disposes of common shares worth $742,586.86","url":"https://stock-news.laohu8.com/highlight/detail?id=2633924533","media":"Reuters","labels":["shareholding","insiderTrades"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2633924533?lang=en_us&edition=fundamental","pubTime":"2026-05-06 04:37","pubTimestamp":1778013465,"startTime":"0","endTime":"0","summary":"Ionis Pharmaceuticals director Joseph Klein III sold 10,111 shares on May 1, 2026, cutting direct holdings to 11,014 shares.Sale followed exercise of 10,111 non-qualified stock options at USD 47.11 per share.Disposals were reported at weighted average prices of USD 73.35 for 8,680 shares, USD 74.45 for 1,431 shares.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Ionis Pharmaceuticals Inc. published the original content used to generate this news brief via EDGAR, the Electronic Data Gathering, Analysis, and Retrieval system operated by the U.S. Securities and Exchange Commission , on May 05, 2026, and is solely responsible for the information contained therein.","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260505:nNDL4fl363:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":"Ionis director Joseph Klein III disposes of common shares worth $742,586.86","news_tag":"shareholding,insiderTrades","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2632937486","title":"Ionis Pharmaceuticals announces virtual annual shareholder meeting","url":"https://stock-news.laohu8.com/highlight/detail?id=2632937486","media":"Reuters","labels":["conferences"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2632937486?lang=en_us&edition=fundamental","pubTime":"2026-05-04 19:06","pubTimestamp":1777892785,"startTime":"0","endTime":"0","summary":"Ionis Pharmaceuticals will hold a virtual Annual Meeting of Stockholders on June 4, 2026.Meeting will be followed by a virtual general corporate update.Corporate update set to include remarks from CEO Brett P. Monia, followed by a Q&A session.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Ionis Pharmaceuticals Inc. published the original content used to generate this news brief via Business Wire  on May 04, 2026, and is solely responsible for the information contained therein.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260504:nNDL40wRp0:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"conferences","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2632933138","title":"A Look At Ionis Pharmaceuticals (IONS) Valuation After FDA Priority Review Wins And Upgraded Revenue Guidance","url":"https://stock-news.laohu8.com/highlight/detail?id=2632933138","media":"Simply Wall St.","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2632933138?lang=en_us&edition=fundamental","pubTime":"2026-05-04 13:13","pubTimestamp":1777871595,"startTime":"0","endTime":"0","summary":"Ionis Pharmaceuticals (IONS) has been in focus after a busy stretch that included US FDA Priority Review and Breakthrough Therapy designations for partner drug bepirovirsen, additional positive zilganersen data in Alexander disease, and a first quarter earnings update.\nSee our latest analysis for Ionis Pharmaceuticals.\nThe recent FDA designations for bepirovirsen, encouraging zilganersen data and raised 2026 revenue guidance help explain why Ionis Pharmaceuticals has a 1-year total...","market":"sg","thumbnail":"https://images.simplywall.st/asset/industry/6111000-choice2-main-header/1585186599552","type":0,"news_type":0,"thumbnails":["https://images.simplywall.st/asset/industry/6111000-choice2-main-header/1585186599552"],"rights":{"source":"simplywall_highlight","url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-ions/ionis-pharmaceuticals/news/a-look-at-ionis-pharmaceuticals-ions-valuation-after-fda-pri","rn_cache_url":null,"directOrigin":true},"property":["rate","earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-ions/ionis-pharmaceuticals/news/a-look-at-ionis-pharmaceuticals-ions-valuation-after-fda-pri","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"simplywall_highlight","symbols":["LABU","IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2632619905","title":"Ionis to present at Bank of America health care conference fireside chat","url":"https://stock-news.laohu8.com/highlight/detail?id=2632619905","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2632619905?lang=en_us&edition=fundamental","pubTime":"2026-05-01 19:05","pubTimestamp":1777633514,"startTime":"0","endTime":"0","summary":"Ionis management will join a fireside chat at Bank of America Securities 2026 Health Care Conference on May 12, 2026.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Ionis Pharmaceuticals Inc. published the original content used to generate this news brief via Business Wire  on May 01, 2026, and is solely responsible for the information contained therein.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260501:nNDL6lkwPN:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU1868837300.USD","IE00BSNM7G36.USD","LU0345770993.USD","LU2471134879.HKD","BK4533","GSX","LU2237443978.SGD","IE0034235188.USD","IE00BFXG1179.USD","IE0002270589.USD","BK4552","LU2750360997.AUD","BK4585","LU2237443549.SGD","BK4588","IE0004091025.USD","LU2471134952.CNY","LU2750360641.GBP","BK4127","LU2237443465.HKD","LU0048573561.USD","LU0345770308.USD","LU1668664300.SGD","LU1804176565.USD","LU1868836591.USD","LU0106831901.USD","LU1894683348.USD","LU2237443382.USD","BK4139","IE00B19Z3581.USD","LU2471134796.USD","LU1868836914.USD","LU2237443895.HKD","LU1868836757.USD","LU1894683264.USD","LU2265009873.SGD","LU2237438978.USD","BK4550","LU0251131958.USD","BK4504","IONS","LU0061475181.USD","LU1791807156.HKD","LU0096364046.USD","LU0251142724.SGD","BK4516","LU0742534661.SGD","LU2471134523.USD","LU1868837136.USD","IE00B19Z3B42.SGD"],"isVideo":false,"video":null,"gpt_icon":0}],"pageSize":20,"totalPage":10,"pageCount":10,"totalSize":200,"code":"91000000","status":"200"}]}}