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Ionis Pharmaceuticals

55.65

-0.3700-0.66%

Post-market: 55.650.00000.00%19:30 EDT

Volume:3.06M

Turnover:169.31M

Market Cap:9.25B

PE:-15.99

High:55.77

Open:55.75

Low:54.91

Close:56.02

52wk High:86.74

52wk Low:50.01

Shares:166.18M

Float Shares:161.92M

Volume Ratio:0.73

T/O Rate:1.89%

Dividend:- -

Dividend Rate:- -

EPS(TTM):-3.4800

EPS(LYR):-2.3812

ROE:-105.50%

ROA:-12.42%

PB:21.03

PE(LYR):-23.37

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Overview Company News Filings

Novartis announces Phase 3 pelacarsen study did not meet primary endpoint

Ionis-Novartis Heart Drug Misses Main Goal of Late-Stage Trial

Novartis Says Pelacarsen Heart Disease Drug Missed Primary Endpoint

Ionis Pharmaceuticals: Buy Rating Backed by FDA Approval of Zanvastro and Strengthened Neurology Pipeline Upside

Movement Alert｜Ionis Pharmaceuticals Falls 9.43% in After-Hours Trading, FDA Approval of Alexander Disease Drug Triggers Sell-the-News Reaction

Ionis Pharmaceuticals (IONS) Receives a Rating Update from a Top Analyst

This Biotech Wins a Big FDA Approval. Why Wall Street is Shrugging.

Analysts’ Opinions Are Mixed on These Healthcare Stocks: cbdMD (YCBD) and Ionis Pharmaceuticals (IONS)

Ionis Pharmaceuticals' Zanvastro Approval Sets Path for Independent Neurology Business, Oppenheimer Says

MT Newswires Live

Ionis Pharmaceuticals Exec Says Zanvastro Will be Available at List Price of $285,000 Per Dose

THOMSON REUTERS

U.S. Stocks on the MOVE-Lululemon Athletica, Adobe, Ionis Pharmaceuticals

Ionis Pharmaceuticals (IONS) Receives a Hold from BMO Capital

Ionis Pharmaceuticals Price Target Maintained with a $115.00/Share by HC Wainwright & Co.

Ionis Pharma up After US FDA Approves Rare Brain Disorder Treatment

Ionis Pharmaceuticals Gets FDA Approval for Alexander Disease Treatment

MT Newswires Live

U.S. Research Roundup-Ciena Corp, Docusign, Snowflake

Ionis Pharmaceuticals, Inc. : Jefferies Cuts Target Price to $88 from $90

THOMSON REUTERS

US FDA Approves Ionis Pharma's Therapy to Treat Rare Genetic Disorder

FDA: Approves Zanvastro (Zilganersen) Injection for Treatment of Alexander Disease in Pediatric and Adult Patients

THOMSON REUTERS

Movement Alert｜Ionis Pharmaceuticals Falls 5.06% in Regular Trading, Trading at $58.215

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Ionis shares were flat.","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4578","PPH","LU0211331839.USD","LU0208291251.USD","IE0009355771.USD","IE00BFTCPJ56.SGD","NVS","BK4139","IE00B2B36J28.USD","IONS","IE00BJT1NW94.SGD","BK4532","IE0002141913.USD","IE00BJJMRZ35.SGD","BK4585","LU0320765489.SGD","BK4007","BK4588","MEDX","LU0070302665.USD","IE00B4R5TH58.HKD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2665351966","title":"Ionis Pharmaceuticals: Buy Rating Backed by FDA Approval of Zanvastro and Strengthened Neurology Pipeline Upside","url":"https://stock-news.laohu8.com/highlight/detail?id=2665351966","media":"TIPRANKS","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2665351966?lang=en_us&edition=fundamental","pubTime":"2026-09-05 04:35","pubTimestamp":1788554117,"startTime":"0","endTime":"0","summary":"William Blair analyst Myles Minter has reiterated their bullish stance on IONS stock, giving a Buy rating today. Myles Minter has given his Buy rat...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/ratings/ionis-pharmaceuticals-buy-rating-backed-by-fda-approval-of-zanvastro-and-strengthened-neurology-pipeline-upside-ratings-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/ratings/ionis-pharmaceuticals-buy-rating-backed-by-fda-approval-of-zanvastro-and-strengthened-neurology-pipeline-upside-ratings-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["IONS","LABU"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1142505378","title":"Movement Alert｜Ionis Pharmaceuticals Falls 9.43% in After-Hours Trading, FDA Approval of Alexander Disease Drug Triggers Sell-the-News Reaction","url":"https://stock-news.laohu8.com/highlight/detail?id=1142505378","media":"Market Focus","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1142505378?lang=en_us&edition=fundamental","pubTime":"2026-09-05 04:34","pubTimestamp":1788554057,"startTime":"0","endTime":"0","summary":"On September 5, Ionis Pharmaceuticals fell 9.43% in after-hours trading, trading at $55.35 per share, with turnover of approximately $2.1 million.On the news front, the FDA on September 4 officially...","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":"Ionis Falls on Sell-the-News After FDA Approves Zanvastro","news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2665353911","title":"Ionis Pharmaceuticals (IONS) Receives a Rating Update from a Top Analyst","url":"https://stock-news.laohu8.com/highlight/detail?id=2665353911","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2665353911?lang=en_us&edition=fundamental","pubTime":"2026-09-05 00:15","pubTimestamp":1788538518,"startTime":"0","endTime":"0","summary":"In a report released today, Yaron Werber from TD Cowen reiterated a Buy rating on Ionis Pharmaceuticals, with a price target of $94.00. According t...","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/ionis-pharmaceuticals-ions-receives-a-rating-update-from-a-top-analyst-blurbs-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/ionis-pharmaceuticals-ions-receives-a-rating-update-from-a-top-analyst-blurbs-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2665935360","title":"This Biotech Wins a Big FDA Approval. 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cbd...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/analysts-opinions-are-mixed-on-these-healthcare-stocks-cbdmd-ycbd-and-ionis-pharmaceuticals-ions-blurbs-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/analysts-opinions-are-mixed-on-these-healthcare-stocks-cbdmd-ycbd-and-ionis-pharmaceuticals-ions-blurbs-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["LU0128526141.USD","BK4581","XBI","YCBD","BK4139","BK4588","BK4007","LABU","LU0029874061.USD","HCSG","IONS","XLV","BK4137","BK4585"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2664849358","title":"Ionis Pharmaceuticals' Zanvastro Approval Sets Path for Independent Neurology Business, Oppenheimer Says","url":"https://stock-news.laohu8.com/highlight/detail?id=2664849358","media":"MT Newswires Live","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2664849358?lang=en_us&edition=fundamental","pubTime":"2026-09-04 23:10","pubTimestamp":1788534632,"startTime":"0","endTime":"0","summary":"Ionis Pharmaceuticals (IONS) has established its first independently commercialized neurology asset with the approval of Zanvastro for Alexander disease, Oppenheimer said in a Friday note.The US Food 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19:36","pubTimestamp":1788521808,"startTime":"0","endTime":"0","summary":"BUZZ-U.S. STOCKS ON THE MOVE-Lululemon Athletica, Adobe, Ionis PharmaceuticalsSeptember 4 (Reuters)-Futures tracking the tech-heavy Nasdaq 100 and the benchmark S&P 500 indexes rose on Friday ahead 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Pharmaceuticals (IONS) Receives a Hold from BMO Capital","url":"https://stock-news.laohu8.com/highlight/detail?id=2664339557","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2664339557?lang=en_us&edition=fundamental","pubTime":"2026-09-04 19:16","pubTimestamp":1788520564,"startTime":"0","endTime":"0","summary":"In a report released today, David Lebowitz from BMO Capital maintained a Hold rating on Ionis Pharmaceuticals, with a price target of $61.00. In ad...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/ionis-pharmaceuticals-ions-receives-a-hold-from-bmo-capital-blurbs-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/ionis-pharmaceuticals-ions-receives-a-hold-from-bmo-capital-blurbs-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4139","IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2664357653","title":"Ionis Pharmaceuticals Price Target Maintained with a $115.00/Share by HC Wainwright & 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Pharmaceuticals  said late Thursday the US Food and Drug Administration approved zanvastrotm, or zilganersen, to treat Alexander disease in pediatric and adult patients.The treatment will be available in the US in the coming weeks, according to the company.A zanvastrotm trial met its primary endpoint in individuals aged at least five years, with the 50-milligram dose showing \"statistically significant and clinically meaningful\" stabilization of gait speed, compared with control at week 61, Ionis said.Alexander disease is an ultra-rare, progressive and often fatal neurological disorder that can affect motor, cognitive, autonomic and gastrointestinal function.The company's shares were up 1.5% in premarket activity 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