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Sionna Therapeutics

7.48

+0.18002.47%

Pre-market: 7.45-0.0300-0.40%07:02 EDT

Volume:766.43K

Turnover:5.72M

Market Cap:336.59M

PE:-3.45

High:7.55

Open:7.27

Low:7.17

Close:7.30

52wk High:54.97

52wk Low:4.01

Shares:45.00M

Float Shares:16.73M

Volume Ratio:0.63

T/O Rate:4.58%

Dividend:- -

Dividend Rate:- -

EPS(TTM):-2.1683

EPS(LYR):-1.8835

ROE:-32.34%

ROA:-21.54%

PB:1.27

PE(LYR):-3.97

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News

Vertex Has Multiple Portfolio Catalysts With Favorable Risk-Reward, RBC Says

MT Newswires Live

Why Sionna Therapeutics (SION) Is Down 90.9% After Ending SION-719 Add-On To Trikafta Therapy

Simply Wall St.

Sionna Therapeutics price target lowered to $5 from $38 at Freedom Broker

Sionna Therapeutics Cut to Neutral from Buy by BTIG

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Sionna Therapeutics (SION) Is Down 90.9% After Ending SION-719 Add-On To Trikafta Therapy","url":"https://stock-news.laohu8.com/highlight/detail?id=2658946453","media":"Simply Wall St.","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2658946453?lang=en_us&edition=fundamental","pubTime":"2026-08-12 04:34","pubTimestamp":1786480479,"startTime":"0","endTime":"0","summary":"Sionna Therapeutics recently reported that its Phase 2a PreciSION CF trial of NBD1 stabilizer SION-719 added to Trikafta did not improve sweat chloride levels, leading the company to discontinue SION-719 as an add-on therapy and to reassess its clinical plans.\nAt the same time, early data from SION-451 combination studies and a cash balance of about US$268.3 million give Sionna room to reconsider how it pursues cystic fibrosis therapies while preserving capital.\nWe’ll now examine how...","market":"nz","thumbnail":"https://images.simplywall.st/asset/industry/6111000-choice1-main-header/1585186710114","type":0,"news_type":0,"thumbnails":["https://images.simplywall.st/asset/industry/6111000-choice1-main-header/1585186710114"],"rights":{"source":"simplywall_highlight","url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-sion/sionna-therapeutics/news/why-sionna-therapeutics-sion-is-down-909-after-ending-sion-7","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-sion/sionna-therapeutics/news/why-sionna-therapeutics-sion-is-down-909-after-ending-sion-7","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"simplywall_highlight","symbols":["SION","AIPO","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2658792916","title":"Sionna Therapeutics price target lowered to $5 from $38 at Freedom Broker","url":"https://stock-news.laohu8.com/highlight/detail?id=2658792916","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2658792916?lang=en_us&edition=fundamental","pubTime":"2026-08-11 22:15","pubTimestamp":1786457710,"startTime":"0","endTime":"0","summary":"Freedom Broker analyst Ilya Zubkov lowered the firm’s price target on Sionna Therapeutics (SION) to $5 from $38 and keeps a Hold rating on the shar...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/sionna-therapeutics-price-target-lowered-to-5-from-38-at-freedom-broker-thefly-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/sionna-therapeutics-price-target-lowered-to-5-from-38-at-freedom-broker-thefly-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["SION"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2658991383","title":"Sionna Therapeutics Cut to Neutral from Buy by BTIG","url":"https://stock-news.laohu8.com/highlight/detail?id=2658991383","media":"Dow Jones","labels":["executive"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2658991383?lang=en_us&edition=fundamental","pubTime":"2026-08-11 18:16","pubTimestamp":1786443360,"startTime":"0","endTime":"0","summary":"Ratings actions from Benzinga: https://www.benzinga.com/quote/SION/analyst-ratings","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"executive","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["SION"],"isVideo":false,"video":null,"gpt_icon":0}],"pageSize":4,"totalPage":32,"pageCount":1,"totalSize":125,"code":"91000000","status":"200"}],"@#url:\"https://hq.skytigris.cn/market/plate/belongs/SION\",params:#limit:6,delay:false,,,undefined,":[]}}